FCROS statistics

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Citations per year

Number of citations per year for the bioinformatics software tool FCROS

Tool usage distribution map

This map represents all the scientific publications referring to FCROS per scientific context
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FCROS specifications


Unique identifier OMICS_02234
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
License GNU General Public License version 2.0
Computer skills Advanced
Version 1.5.6
Stability Stable
Maintained Yes


No version available


Publication for FCROS

FCROS citations


Robust volcano plot: identification of differential metabolites in the presence of outliers

BMC Bioinformatics
PMCID: 5896081
PMID: 29642836
DOI: 10.1186/s12859-018-2117-2

[…] e primarily been used to identify differential metabolites: (i) classical parametric approaches, such as Student’s t-test [], classical volcano plot (CVP) [] and fold change rank ordering statistics (FCROS) [], (ii) classical non-parametric approaches, such as significance analysis of microarrays (SAM) [], and the Wilcoxon [] and Kruskal-Wallis (K-W) [] tests, (iii) Bayesian parametric approaches, […]


Semi quantitative proteomics of mammalian cells upon short term exposure to non ionizing electromagnetic fields

PLoS One
PMCID: 5325209
PMID: 28234898
DOI: 10.1371/journal.pone.0170762

[…] as up-regulated upon ELF exposure. Furthermore, we ranked the statistical methods according to the numbers of regulated proteins detected: RankProd returned the largest set (38 proteins), followed by fcros (21 proteins), M-score (19 proteins), fold-change assessed with peak intensity-based significance B (4 proteins), Z-score (2 proteins) and limma/TREAT (1 protein). About one-third of the differe […]


Comments on: fold change rank ordering statistics: a new method for detecting differentially expressed genes

BMC Bioinformatics
PMCID: 5111201
PMID: 27846811
DOI: 10.1186/s12859-016-1322-0

[…] To search for differentially expressed (DE) genes in profiling studies, we presented a new method based on fold change rank ordering statistics (FCROS). For the derivation of this method, we considered microarrays data from two biological conditions where n probes (genes) were used with m 1 control and m 2 test samples. We performed k pairwise […]


Mof associated complexes have overlapping and unique roles in regulating pluripotency in embryonic stem cells and during differentiation

PMCID: 4059888
PMID: 24898753
DOI: 10.7554/eLife.02104.025

[…] version 1.1 to calculate probe set signal intensities using Robust Multi-array Average (RMA) algorithms with default settings.To select the DE genes, we used the fold change rank ordering statistics (FCROS) method (). In the FCROS method, k pairs of test/control samples are used to compute fold changes (FC). For each pair of test/control samples, obtained FCs for all genes are ranked in increasing […]

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FCROS institution(s)
Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR 7104, Université de Strasbourg, Illkirch, France

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