Computational protocol: Effects of early feeding on growth velocity and overweight/obesity in a cohort of HIV unexposed South African infants and children

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Protocol publication

[…] Standardised questionnaires were used to collect interview data during pregnancy and postnatally at 3, 6, 12 and 24 weeks, and at the primary endpoint of 2 years of age. Maternal variables included: age, parity and education which were captured during recruitment; delivery mode and reported HIV status collected at the 3 week visit. The questionnaires also addressed infant feeding practices through 24-hour and 7-day recall of a list of 23 foods commonly consumed in the study sites. No food diaries were used. Data on child birth weight were extracted from perinatal records.Field staff measured child weight and recumbent length/height during the 3, 6, 12, and 24 weeks visits and at 2 years. Children were weighed to the nearest 0.1 kg on Masskot (SOS Series) electronic pan scales, which were calibrated weekly using a 2 kg weight, wearing minimum clothing and no shoes. Depending on the study site, recumbent length measurements were obtained to the nearest 0.1 cm using TALC roller meters (Oxford, UK) or Shorr Height-Length Measuring Board (Maryland, USA) while height was measured using a validated ustom-made stadiometer. All field workers were trained on anthropometric techniques. In order to improve validity and reduce inter and intra-observer bias, the anthropometry data collection was validated periodically. Child age was calculated using the date of birth from the Road to Health card and the date of the interview.Data were double-entered into a Microsoft Access database and analysed using Stata SE 12 [] and IBM SPSS Statistics 21 []. […]

Pipeline specifications

Software tools Stata, SPSS
Application Miscellaneous
Organisms Human immunodeficiency virus 2, Homo sapiens