|Dataset type:||Expression profiling by high throughput sequencing, Other|
|Number of samples:||14|
|Release date:||Jan 7 2019|
|Last update date:||Feb 19 2019|
|Dataset link||Translation control of the immune checkpoint in cancer and its therapeutic targeting|
To identify the transcripts specifically translated in primary liver tumors in MYC; KRAS(G12D) and KRAS(G12D) mice, we first carefully micro-dissected primary liver tumor nodules in MYC; KRAS(G12D) and KRAS(G12D) mice as well as wildtype (WT) controls. We sequenced total mRNAs (2 replicates each) and ribosome-protected mRNA fragments (RPFs) using ribosome profiling (2 replicates each) to generate genome-wide transcriptional and translational landscapes, respectively.