Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 17
Release date: Aug 30 2014
Last update date: May 11 2017
Access: Public
Taxon: Mus musculus
Computational protocol: RUM, DESeq
Dataset link Paternal poly(ADP-ribose) metabolism modulates retention of inheritable sperm histones and early embryonic gene expression [PJ34_2CE]

Experimental Protocol


Seven WT (wild-type) samples of one 2-cell embryo each, all from fathers treated with saline (controls). Each group A, B, D consists of eggs fertilized by the same father (each sample is a single 2 cell embryo, 2CE). Ten samples of 2CE from fathers treated with PJ34 (PARP inhibitor) for 6 weeks, in the same setup (PJ-MTM11-1 to PJ34-MTM14-2, offspring from fathers MTM11, MTM13 or MTM14). All mice are wild-type, strain 129SVE (=129S6/SvEvTac, Taconic).

Repositories


GEO

GSE56182

ArrayExpress

E-GEOD-56182

BioProject

PRJNA242651

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Contact


Ralph Meyer
Ralph G Meyer

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