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Fluorescence in situ hybridization probe design software tools | Laser scanning microscopy image analysis

Fluorescence in situ hybridization probe design software tools | Laser scanning microscopy image analysis Though a formidable portfolio of ready-to-use probes is available from various commercial sources, the choice is usually restricted to a relatively small number (<200) of loci mostly belonging to the human genome. Probes targeting other loci or species can be developed from genomic DNA fragments cloned in bacterial artificial chromosomes (BACs) and fosmids, or using array-based technology. However, implementing these methods in-house or outsourcing them to commercial parties can be challenging if not impossible for many laboratories for both logistic and economic reasons.
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