Flow cytometry data analysis software tools
Flow cytometry is a technology widely used in clinical practice and in research, particularly in the field of immunology. It is capable of interrogating a wide variety of markers on many different cell types on a single-cell basis, using fluorophore-conjugated antibodies. Although molecular as well as genomic studies have advanced the understanding of immunological processes and autoimmune diseases, the components of the human immune system and their functions have yet to be comprehensively described. Without such a reference “catalog” of the immune system, it is ultimately difficult to interpret the pathogenic significance of genetic, molecular, or phenotypic variants observed in diseases.
(Hu et al., 2013) Application of user-guided automated cytometric data analysis to large-scale immunoprofiling of invariant natural killer T cells. PNAS.