flowCL

Performs semantic labelling of cell populations based on their surface markers and applied it to labelling of the Federation of Clinical Immunology Societies Human Immunology Project Consortium lyoplate populations as a use case. flowCL enables researchers to unambiguously label their cell populations based on their immunophenotype using the CL and allows for unambiguous and reproducible identification of standardized cell types. It decomposes a query such as ‘CD4+CD8−’ (as provided in the conventional format used by immunologists) into its individual markers (CD4, CD8) and translates their relative abundance into a relation used in the CL, such as + for has plasma membrane part. As the CL development proceeds, flowCL automatically remains up-to-date with the latest scientific knowledge.