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flowClust specifications


Unique identifier OMICS_05595
Name flowClust
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
License Artistic License version 2.0
Computer skills Advanced
Version 3.18.0
Stability Stable
methods, BiocGenerics, Biobase, testthat, ellipse, graph, RBGL, R(>=2.5.0), flowCore, flowViz, MCMCpack, clue, mnormt, flowWorkspace, flowWorkspaceData
Maintained Yes


No version available


Publication for flowClust

flowClust citations


NKG2C+ memory like NK cells contribute to the control of HIV viremia during primary infection: Optiprim ANRS 147

PMCID: 5539415
PMID: 28791125
DOI: 10.1038/cti.2017.22

[…] The flowClust implementation version 3.4.11 on R version 3.1.2 (R foundation for Statistical Computing, Vienna, Austria) under Linux Cent OS 6, was applied on the following parameters: CD56-PC7, CD16-APCH […]


A Mature NK Profile at the Time of HIV Primary Infection Is Associated with an Early Response to cART

Front Immunol
PMCID: 5300971
PMID: 28239376
DOI: 10.3389/fimmu.2017.00054

[…] The flowClust implementation version 3.4.11on R version 3.1.2 under Linux Cent OS 6 was applied on the following parameters: CD56-PC7, CD16-APCH7, NKG2A-PacBlue, NKG2C-PE, CD57-FITC, to compute clusters a […]


TGF β Affects the Differentiation of Human GM CSF+ CD4+ T Cells in an Activation and Sodium Dependent Manner

Front Immunol
PMCID: 5179518
PMID: 28066414
DOI: 10.3389/fimmu.2016.00603

[…] he following settings: maximum number of iterations = 10,000, perplexity = 258 (that is 10% of the total number of data points), theta = 0 (exact t-SNE).Model-based clustering was performed using the flowClust (, ) R package with the following settings: Gaussian mixture models were used (ν = ∞), convergence tolerance of expectation-maximization (EM) = 10−15, maximum number of EM iterations = 10 00 […]


Immunophenotype Discovery, Hierarchical Organization, and Template Based Classification of Flow Cytometry Samples

PMCID: 5005935
PMID: 27630823
DOI: 10.3389/fonc.2016.00188

[…] , ), and (5) categorizing samples into distinct classes and identifying phenotypes (, , ). A number of open-source R packages have been developed to solve different steps, such as flowCore, flowViz, flowClust, flowTrans, flowStats, and flowType packages in Bioconductor (). Several other web-based platforms are also available for automated FC data analysis, such as ImmPort (), GenePattern (), and […]


MEMO: multi experiment mixture model analysis of censored data

PMCID: 4978932
PMID: 27153627
DOI: 10.1093/bioinformatics/btw190

[…] is receiving increasing attention due to a rising number of single-cell technologies (; ; ; ). Standard approaches are well established (; ), and several software packages are available. FLAME () and flowClust () enable Gaussian, t and skew t mixture modeling of flow cytometry data and can also be used for other data types. In these implementations, multiple samples are handled using metaclusterin […]


Increased NK Cell Maturation in Patients with Acute Myeloid Leukemia

Front Immunol
PMCID: 4635854
PMID: 26594214
DOI: 10.3389/fimmu.2015.00564

[…] parameter. New tools are then required to address these problems. Recently, algorithms for automatic gating and 2D mapping of high dimensional dataset have been developed, such as Spade (), viSNE (), flowClust (), or FLOCK (, ). These algorithms combined to classification methods enable the visualization of multiple parameters and summarize information. These approaches are of particular importanc […]


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flowClust institution(s)
Department of Statistics, University of British Columbia, Vancouver, BC, Canada

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