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- person_outline Guanglan Zhang
- person_outline Christian Simon
Publication for FluKB
Incorporating structure context of HA protein to improve antigenicity calculation for influenza virus A/H3N2
[…] from various international databases: The influenza virus resource at the National Center for Biotechnology Information, Global Initiative on Sharing All Influenza Data (http://platform.gisaid.org/), FluKB, Influenza research database and reports from National Institute for Medical Research (http://www.nimr.mrc.ac.uk/). Details can be found in Collection and Data Preprocessing. […]
Big Data Analytics in Immunology: A Knowledge Based Approach
[…] h the online antigen KB. All our knowledgebases have the basic keyword search tools for locating antigens and T-cell epitopes or HLA ligands. The advanced keyword search tool was included in FLAVIdB, FLUKB, and HPVdB, where users further restrict the search by selecting virus species, viral subtype, pathology, host organism, viral strain type, and several other filters. Other analytical tools incl […]
Large Scale Analysis of B Cell Epitopes on Influenza Virus Hemagglutinin – Implications for Cross Reactivity of Neutralizing Antibodies
[…] an overview of binding specificities of reported nAbs, as well as an estimate of their neutralization and escape coverage (neutralization effectiveness) in more than 45,000 HA sequences available in FLUKB. The variety and frequency of discontinuous peptides within different B-cell epitopes have been analyzed in the HA data set. The results of the analysis of discontinuous peptides provide insight […]
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