Find and compare the best bioinformatics software tools for quantifying and analysing fluorescence signal on conventional fluorescence microscopy images. Tools are ranked by the biomedical research community.
Analyzes, processes and visualizes multi-dimensional microscopy images. BioImageXD puts open-source computer science tools for three-dimensional visualization and analysis into the hands of all researchers, through a user-friendly graphical interface tuned to the needs of biologists. BioImageXD has no restrictive licenses or undisclosed algorithms and enables publication of precise, reproducible and modifiable workflows. It allows simple construction of processing pipelines and should enable biologists to perform challenging analyses of complex processes.
A tool for segmentation, fluorescence quantification, and tracking of cells on microscopy images. CellX decodes the information across the cell membrane and guarantees optimal detection of the cell boundaries on a per-cell basis. Graph cuts account for the information of the cell boundaries through directional cross-correlations, and they automatically incorporate spatial constraints. The method accurately segments images of various cell types grown in dense cultures that are acquired with different microscopy techniques.
Performs 2D immunofluorescence images to pinpoint and number synaptic protein puncta. SynPAnal provides an application that intends to partially automate processing tasks of files generated by confocal laser scanning microscopy. The application focuses on the quantification of puncta attributes but can also be applied for basic fluorescent intensity measuring as well as for basic morphometric analysis of neurons.
Deduces multi-feature phenotypic crosstalk from perturbation assays. PHOCOS takes into consideration the potential interactions among different attributes of biomarkers. It can retrieve core, direct-effect motifs from missing links, noise and indirect effects. This tool can produce ‘high-resolution’ views of which phenotypic attributes support interaction among biomarkers. It is useful for microscopy images and others biological datasets.
Investigates digital microscopy images of giant unilamellar vesicles (GUVs). GUV-AP allows users to study membrane dye incorporation and protein binding to membranes. It retrieves circular particles in the microscopy image and determines their centers and radii. This tool is useful for comparing the binding efficiency of proteins to membranes of different compositions and biophysical properties.
You can access more results by creating a free plan account or unlimited content via a premium account.