Main logo
?
tutorial arrow
×
Create your own tool library
Bookmark tools and put favorites into folders to find them easily.

FCF | Flux coupling analysis of genome-scale metabolic network reconstructions

Online

Elucidates the topological and flux connectivity features of genome-scale metabolic networks and enables the global identification of blocked reactions, equivalent knockouts, and sets of affected reactions. The FCF computational procedure allows one to determine whether any two metabolic fluxes, v1 and v2, are (i) fully coupled, if a non-zero flux for v1 implies a non-zero, but also a fixed flux for v2 and vice versa; (ii) partially coupled, if a non-zero flux for v1 implies a non-zero, though variable, flux for v2 and vice versa; or (iii) directionally coupled, if a non-zero flux for v1 implies a non-zero flux for v2 but not necessarily the reverse. Due to its wide range of features and applicability to genome-scale networks, the FCF procedure provides a useful framework for both modelers and experimentalists seeking to extract biologically meaningful information from metabolic reconstructions.

User report

tutorial arrow
×
Vote up tools and offer feedback
Give value to tools and make your expertise visible
Give your feedback on this tool
Sign up for free to join and share with the community

0 user reviews

star_border star_border star_border star_border star_border
star star star star star

0 user reviews

star_border star_border star_border star_border star_border
star star star star star

No review has been posted.

FCF forum

tutorial arrow
×
Communicate with other users
Participate in the forum to get support for using tools. Ask questions about technical specifications.
Take part in the discussion
Sign up for free to ask question and share your advices

No open topic.

FCF classification

FCF specifications

Unique identifier:
OMICS_16112
Software type:
Framework/Library
Restrictions to use:
None
Programming languages:
C++
Stability:
Stable
Name:
Flux Coupling Finder
Interface:
Command line interface
Operating system:
Unix/Linux
Computer skills:
Advanced
Maintained:
Yes

FCF distribution

versioning

tutorial arrow
×
Upload and version your source code
Get a DOI for each update to improve tool traceability. Archive your releases so the community can easily visualize progress on your work.
Facilitate your tool traceability
Sign up for free to upload your code and get a DOI

No versioning.

FCF support

Maintainer

  • Costas Maranas <>

Credits

tutorial arrow
×
Promote your skills
Define all the tasks you managed and assign your profile the appropriate badges. Become an active member.
Promote your work
Sign up for free to badge your contributorship

Publications

Institution(s)

Department of Chemical Engineering, The Pennsylvania State University, University Park, PA, USA; Genomatica Inc., San Diego, CA, USA

Funding source(s)

This work was supported by the NSF Award BES0120277 and the U.S. DOE.

By using OMICtools you acknowledge that you have read and accepted the terms of the end user license agreement.