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It is the leading website and database of Drosophila genes and genomes. FlyBase curates a variety of data from published biological literature, including phenotype, gene expression, interactions (genetic and physical), gene ontology (GO) information and many others. These data are organized in ∼31 different data-type reports such as the Gene Report or the Allele Report. The range of data we provide increases and changes as new types of data become available. Whether you are using the fruit fly Drosophila melanogaster as an experimental system or wish to understand Drosophila biological knowledge in relation to human disease or to other model systems, FlyBase can help you successfully find the information you are looking for.

Restrictions to use:
Data access:
File download, Web user interface, FTP
User data submission:
FlyBase release FB2015_05
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Department of Genetics, University of Cambridge, Downing Street, Cambridge, CB2 3EH, UK; The Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA; Department of Biology, Indiana University, Bloomington, IN 47405, USA

Funding source(s)

FlyBase is supported by a grant from the National Human Genome Research Institute at the U.S. National Institutes of Health U41HG000739. Support is also provided by the British Medical Research Council, the Indiana Genomics Initiative, and the National Science Foundation through XSEDE resources provided by Indiana University.

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  • (Gene Ontology, 2010) The Gene Ontology in 2010: extensions and refinements. Nucleic acids research.
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  • (Reference Genome Group of the Gene Ontology, 2009) The Gene Ontology’s Reference Genome Project: a unified framework for functional annotation across species. PLoS computational biology.
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  • (Loevenich et al., 2009) The Drosophila melanogaster PeptideAtlas facilitates the use of peptide data for improved fly proteomics and genome annotation. BMC bioinformatics.
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  • (Stark et al., 2007) Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures. Nature.
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  • (Lin et al., 2007) Revisiting the protein-coding gene catalog of Drosophila melanogaster using 12 fly genomes. Genome research.
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  • (Mungall et al., 2007) A Chado case study: an ontology-based modular schema for representing genome-associated biological information. Bioinformatics.
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  • (Crosby et al., 2007) FlyBase: genomes by the dozen. Nucleic acids research.
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  • (Grumbling and Strelets, 2006) FlyBase: anatomical data, images and queries. Nucleic acids research.
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  • Animals
    • Drosophila melanogaster

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