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FNC specifications


Unique identifier OMICS_25976
Name FNC
Alternative name Functional Network Connectivity
Software type Application/Script
Interface Graphical user interface
Restrictions to use None
Input data A GIFT parameter file.
Operating system Unix/Linux, Windows
Programming languages MATLAB
Computer skills Medium
Version 2.2
Stability Stable
A GIFT analysis
Registration required Yes
Maintained Yes


No version available



  • person_outline Nathan Swanson
  • person_outline Oguz Demirci

Publications for Functional Network Connectivity

FNC citations


Synchronization within, and interactions between, the default mode and dorsal attention networks in relapsing remitting multiple sclerosis

PMCID: 5957478
DOI: 10.2147/NDT.S155478
call_split See protocol

[…] The FNC was analyzed using the FNC toolbox (v2.3) to determine the temporal correlation between the components (subnetworks) obtained by the ICA. The direct possibility was calculated using the constraine […]


The altered Granger causality connection among pain related brain networks in migraine

PMCID: 5882438
PMID: 29517685
DOI: 10.1097/MD.0000000000010102

[…] lab.mrn.org/software/gift/). After 20 times randlnit and bootstrap and regression operations, we extracted 7 resting-state networks from 3 components, which were SN, DMN, ECN, RFPN, LFPN, SMN, and VN.Functional network connectivity (FNC, http://mialab.mrn.org/software/fnc) software was applied to analyze network causal relationships. Seven resting-state network components were selected and filtere […]


Rest but busy: Aberrant resting‐state functional connectivity of triple network model in insomnia

PMCID: 5822570
PMID: 29484254
DOI: 10.1002/brb3.876
call_split See protocol

[…] ‐Mazoyer et al., ) of the brain regions were summarized in Table .After ICA analysis, we calculated the constrained minimal lagged correlation using the extension of GIFT RRID:SCR_001953 which is the functional network connectivity toolbox (FNC RRID:SCR_015731, http://mialab.mrn.org/software/#fnc) (Jafri et al., ; Xin & Lei, ) to measure the interactions of the four networks. The correlation among […]


Altered effective connectivity of resting state networks by acupuncture stimulation in stroke patients with left hemiplegia

PMCID: 5709020
PMID: 29382021
DOI: 10.1097/MD.0000000000008897

[…] To investigate the causal relationships among the RSNs, functional network connectivity software[] was applied in this study. Seven RSN components identified by ICA were filtered at 0.01– 0.1 Hz and the generalized partial directed coherence was selected a […]


Decreased Triple Network Connectivity in Patients with Recent Onset Post Traumatic Stress Disorder after a Single Prolonged Trauma Exposure

Sci Rep
PMCID: 5626705
PMID: 28974724
DOI: 10.1038/s41598-017-12964-6

[…] course of each subject, each column corresponds to one IC. Based on the identified ICs for CEN, DMN, and SN, the corresponding columns were selected from the time course of each subject and used for FNC analysis. […]


The effect of preprocessing in dynamic functional network connectivity used to classify mild traumatic brain injury

PMCID: 5651393
PMID: 29075569
DOI: 10.1002/brb3.809
call_split See protocol

[…] alab.mrn.org/software/gift/) to obtain a set of functionally independent resting‐state networks (RSN) each one composed of a temporal and a spatial part (Calhoun & Adali, ). As this study deals with dFNC, performed analysis focuses mainly on the temporal information.The optimal number of gICA components was determined to be 70 using a modified version of ICASSO (RRID:SCR_014981; ICASSO was include […]


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FNC institution(s)
The Mind Research Network, Albuquerque, NM, USA; Sony Electronics, Inc., San Jose, CA, USA; Department of Electrical and Computer Engineering, UNM, Albuquerque, NM, USA; Department of Psychiatry, University of Iowa, Iowa City, IA, USA; Olin Neuropsychiatry Research Center, Hartford, CT, USA; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA; Department of Psychology, UNM, Albuquerque, NM, USA; Division of Child and Adolescent Psychiatry, UMN, Minneapolis, MN, USA
FNC funding source(s)
Supported by the National Institutes of Health, under grants 1 R01 EB 000840 and 1 R01 EB 005846.

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