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|Alternative name||Foldit Standalone|
|Interface||Graphical user interface|
|Input format||PDB, FASTA|
|Operating system||Unix/Linux, Mac OS, Windows|
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- person_outline Seth Cooper
Publications for Foldit
Interaction of the GntR family transcription factor Sll1961 with thioredoxin in the cyanobacterium Synechocystis sp. PCC 6803
[…] in detail in Supplementary Text and Supplementary Table . Three-dimensional structure predictions were performed using the I-TASSER server. Docking predictions were performed using the ZDOCK server. Foldit Standalone was used for manual refinement of predicted structures. […]
A Review on the Applications of Crowdsourcing in Human Pathology
[…] tration (e.g., ReCAPTCHA), and learning in education (i.e., incorporating crowdsourcing in the curriculum of courses). Regarding megatasks, authors mentioned two possible forms: hard games (e.g., Foldit and EteRNA), and open innovation contests (e.g., DREAM challenges). They distinguish casual games and hard games according to the incentive for the gamers, which is engagement in repetiti […]
Assemble And Match: A Novel Hybrid Tool for Enhancing Education and Research in Rational Structure Based Drug Design
[…] might be manifested more strikingly in the current version, the prospective tool is expected to provide more efficient screening processes by exploiting the cognitive abilities of humans. Inspired by Foldit, a crowd-sourcing computer game which enables its players to contribute to solving the protein folding problem, we envision that Assemble-And-Match can become a crowd-sourcing physical game for […]
Can human experts predict solubility better than computers?
[…] uld increase or decrease solubility. It might seem surprising that a computer could not, with the advantages described above, outperform a human at such a task. Nonetheless, human participants in the FoldIt project have been able to make useful contributions even in a field as apparently computation-intensive as protein folding, at least once the problem was suitably gamified . Perhaps, some of […]
A cyber linked undergraduate research experience in computational biomolecular structure prediction and design
[…] immune stimulation ; this work continues in the host lab and has enabled new collaborations with experimental labs. Another intern examined the computer–human interface for the protein-folding game FoldIt  to measure how three-star rating systems affect game player persistence . One student designed co-assembling multicomponent protein crystals, and the host lab invited him back for a second […]
Integrative biological simulation praxis: Considerations from physics, philosophy, and data/model curation practices
[…] a brief training period in which they are familiarized with the existing taxonomy, GalaxyZoo was able to classify over 50 million images in the first year, taking advantage of over 150,000 volunteers.FoldIt is an example of a biological open science project that has generated a tremendous amount of data by taking advantage of large numbers of human volunteers. Employing a strategy known as “gamifi […]
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