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FOLy specifications


Unique identifier OMICS_22498
Name FOLy
Alternative name Fungal Oxidative Lignin enzymes database
Restrictions to use None
Community driven No
Data access Browse
User data submission Not allowed
Maintained No


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Publication for Fungal Oxidative Lignin enzymes database

FOLy citations


Metadata Analysis of Phanerochaete chrysosporium Gene Expression Data Identified Common CAZymes Encoding Gene Expression Profiles Involved in Cellulose and Hemicellulose Degradation

PMCID: 5264264
PMID: 28123349
DOI: 10.7150/ijbs.17390

[…] the genes and enzymes involved in cellulose, hemicellulose and lignin degradation mechanisms.Development of online based genome and enzyme databases like CAZy (Carbohydrate Active Enzyme database) , FOLy (Fungal Lignin Oxidizing Enzymes) , DOE-JGI (Joint Genome Institute) and FungiDB etc., has significantly influenced the present understanding of fungal genomic and proteomic studies. The CAZy d […]


Proteogenomic Analysis of a Thermophilic Bacterial Consortium Adapted to Deconstruct Switchgrass

PLoS One
PMCID: 3716776
PMID: 23894306
DOI: 10.1371/journal.pone.0068465

[…] tegrated Microbial Genomes Expert Review (IMG-ER) System –.The protein sequences were also screened for carbohydrate-active enzymes using dbCAN and using blastp against a local copy of the CAZy and FOLy databases (E<1e−20), keeping track of both the best blastp hit overall, and the best hit against any protein in CAZy or FOLy with an experimentally validated EC number. To achieve better coverag […]


The Metagenome of an Anaerobic Microbial Community Decomposing Poplar Wood Chips

PLoS One
PMCID: 3357426
PMID: 22629327
DOI: 10.1371/journal.pone.0036740

[…] divided into 300 nt fragments (tiles) overlapping by 150 nt. BlastX searches of each fragment were then conducted vs. the complete set of protein sequences from the CAZy ( and FOLy ( websites. Contiguous runs of best hits with e-value below a 1e-10 threshold and having the same CAZy or FOLy gene family were collected from each fragment. These r […]


Metatranscriptomics Reveals the Diversity of Genes Expressed by Eukaryotes in Forest Soils

PLoS One
PMCID: 3253082
PMID: 22238585
DOI: 10.1371/journal.pone.0028967

[…] BLASTX searches (default parameters) against various specialized databases. Searches were made against Carbohydrate Active Enzymes (CAZy,; ); and Fungal Oxidative Lignin Enzymes (FOLy;; ) databases to find plant cell wall degradation enzymes. cDNA similar to cytochrome P450 potentially involved in detoxication of plant secondary metabolites were s […]


Fungi Unearthed: Transcripts Encoding Lignocellulolytic and Chitinolytic Enzymes in Forest Soil

PLoS One
PMCID: 2881045
PMID: 20532045
DOI: 10.1371/journal.pone.0010971
call_split See protocol

[…] ic, hemicellulolytic, and chitinolytic enzymes were developed on the basis of reference protein sequences from curated databases like CAZy ( , see also or FOLy ( ), or GenBank. The reference sequences were compared against the NCBI database standard protein-protein BLAST (blastp) (), and the distance tree option implemented […]


Targeted Discovery of Glycoside Hydrolases from a Switchgrass Adapted Compost Community

PLoS One
PMCID: 2809096
PMID: 20098679
DOI: 10.1371/journal.pone.0008812

[…] oducing higher depth contigs will be weighted in the analysis).To extract potential full-length glycoside hydrolases from the metagenome data, we ran BLASTX on all contigs ≥1 kb against the CAZy and FOLy databases (E<1e−10), and filtered out hits matching the target enzyme over at least 90% of its length, and for which the target enzyme has a known enzymatic function (EC number listed in CAZy or […]


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FOLy institution(s)
MR 1163 INRA de Biotechnologie des Champignons Filamenteux, IFR86-BAIM, Université de Provence et de la Méditerranée, ESIL, Marseille, France; Laboratoire de Phylogénomique, EA 3781 Evolution Biologique Université de Provence, Marseille, France; Glycogenomics and Biomedical Structural Biology, AFMB Laboratory—UMR 6098—CNRS Université d’Aix-Marseille I et II, Marseille, France
FOLy funding source(s)
Supported by the sixth European Framework Program for Research and Technological Development (FP6) and BIORENEW (026456).

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