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Forge specifications


Unique identifier OMICS_20673
Name Forge
Alternative name Cresset Forge
Software type Toolkit/Suite
Interface Command line interface, Graphical user interface
Restrictions to use License purchase required
Operating system Unix/Linux, Mac OS, Windows
Computer skills Advanced
Version 10.4
Stability Stable
Free trial Yes
Registration required Yes
Maintained Yes


  • Activity Atlas
  • Activity Miner
  • CressetEngineBroker
  • FieldTemplater
  • k-nearest Neighbour


No version available



  • person_outline Cresset Team

Forge citations


Schizophrenia and Category Selectivity in the Brain: Normal for Faces but Abnormal for Houses

PMCID: 5829027
PMID: 29527179
DOI: 10.3389/fpsyt.2018.00047

[…] left PPA (x = −27; y = −64; z = −11; ext = 433), and right PPA (x = 30; y = −52; z = −8; ext = 409) ROIs. ROIs were based on the maximum-probability maps from the freely available probabilistic Brain Activity Atlas [BAA (, )]. For the FFA ROIs, we combined the anterior and posterior FFA ROIs from the BAA into combined FFA ROIs (one for each hemisphere). Details are described in the Supplementary M […]


MAP Kinase Phosphatase 3 (MKP3) Preserves Norepinephrine Transporter Activity by Modulating ERK1/2 Kinase Mediated Gene Expression

PMCID: 5572231
PMID: 28878626
DOI: 10.3389/fncel.2017.00253

[…] ing events that determine neurotransmitter transporter activity. As mentioned above experiments have established that intracellular NET can be recruited to the cell surface in states of high neuronal activity (Miner et al., ) and depolarization results in increased NET activity (Mandela and Ordway, ). This result implies that surface expression of NET is highly regulated. We believe the process we […]


3D QSAR studies on Maslinic acid analogs for Anticancer activity against Breast Cancer cell line MCF 7

Sci Rep
PMCID: 5519539
PMID: 28729623
DOI: 10.1038/s41598-017-06131-0
call_split See protocol

[…] As no structural information is currently available for maslinic acid in its target-bound state, therefore FieldTemplater module of Forge v10 (Cresset Inc., UK) software was used to determine a hypothesis for the 3D conformation. For this, the field and shape information were used by the template through c […]


A Multi Atlas Labeling Approach for Identifying Subject Specific Functional Regions of Interest

PLoS One
PMCID: 4721956
PMID: 26796546
DOI: 10.1371/journal.pone.0146868

[…] The functional atlas database for face recognition, which is part of the Brain Activity Atlas project (, was used in this study. In the database, the subject-specific FSRs had been manually labeled for 202 participants (age: 18–23, 124 female) [ […]


Discovery of Small Molecules that Inhibit the Disordered Protein, p27Kip1

Sci Rep
PMCID: 4623604
PMID: 26507530
DOI: 10.1038/srep15686

[…] Consensus field maps for Group 1 and 2 molecules were defined using the FieldTemplater module in Forge (v10, Cresset, REF= Dec 2014). The FieldTemplater module takes as input a set of reference molecules (the active compounds for Groups 1 and 2 identified in the first two rounds of screening; ) and seeks to align them in order to maximi […]


Development of Small Molecule Cryptochrome Stabilizer Derivatives as Modulators of the Circadian Clock

PMCID: 4576822
PMID: 26174033
DOI: 10.1002/cmdc.201500260

[…] a so-called “pharmacophore”, to identify structural regions in the ligands crucial for bioactivity. In our study, field points of KL001 and KL044 were used for generating a pharmacophore (Figure ) in FieldTemplater available in the Forge software package, which was used to align a diverse range of KL001 derivatives. The data included a set of 60 compounds with their potency in terms of −log(EC50) […]


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Forge institution(s)
Cresser, New Cambridge House, Cambridgeshire, UK

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