FragFit statistics

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FragFit specifications


Unique identifier OMICS_29905
Name FragFit
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Peter Hildebrand <>

Publication for FragFit

FragFit in publications

PMCID: 5683378
PMID: 29132296
DOI: 10.1186/s12859-017-1904-5

[…] are now demanded., here we investigated and benchmarked the suitability of a classical and well established fragment-based approach for modeling of segments into cryo-em density maps (termed fragfit). fragfit uses a hierarchical strategy to select fragments from a pre-calculated set of billions of fragments derived from structures deposited in the protein data bank, based on sequence […]

PMCID: 4783127
PMID: 26973877
DOI: 10.1126/sciadv.1501502

[…] end was built manually into the derived density in coot (), and the initial fitting was globally idealized using erraser (). the structure of poorly resolved, flexible loops in if2 was predicted by fragfit, a fragment-based tool for modeling of missing protein segments into cryo-em density maps (see section below). these initial models were then refined by real-space refinement in phenix 1.10. […]

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FragFit institution(s)
Institute of Medical Physics and Biophysics, Charite University Medicine Berlin, Berlin, Germany; Institute of Medical Physics and Biophysics, Medical University Leipzig, Leipzig, Sachsen, Germany
FragFit funding source(s)
Supported by Deutsche Forschungsgemeinschaft [SFB740/B6, HI 1502/1–2, BI 893/8, SFB740/Z1], Berlin Institute of Health, Stiftung Charite and Einstein Center Digital Future.

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