fRMA protocols

fRMA specifications

Information


Unique identifier OMICS_01994
Name fRMA
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
License GNU General Public License version 2.0
Computer skills Advanced
Stability Stable
Maintained Yes

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Documentation


Maintainer


  • person_outline Matthew McCall <>

Publication for fRMA

fRMA IN pipelines

 (2)
2017
PMCID: 5493619
PMID: 28667284
DOI: 10.1038/s41598-017-04400-6

[…] ad, gbm and lc (supplementary table s9). studies undertaken on ht hg u133a, hg u133a, and hg u133plus2 affymetrix microarray platforms were selected to allow the frozen robust multiarray analysis (frma) normalization method to be used and to reduce inter-platform differences65., following steps defined previously66, disease-specific meta-analyses were conducted to increase the statistical […]

2017
PMCID: 5493619
PMID: 28667284
DOI: 10.1038/s41598-017-04400-6

[…] disease-specific meta-analyses were conducted to increase the statistical significance and to minimize the noise intrinsic to gene expression measurements. microarray datasets were normalized using frma61 from the r affy package67. when multiple probes matched the same gene symbol, probes presenting the greatest inter-quartile range were selected. only genes present in all the selected […]

fRMA institution(s)
Department of Biostatistics and Computational Biology, University of Rochester Medical Center, CU, Chinahester, NY, USA

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