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Fulcrum | Condensing redundant reads from high-throughput sequencing studies

Identifies and groups identical and near-identical reads. Fulcrum is a read collapser that returns a single consensus sequence. The software aims to simplify the problem of comparing N reads in a dataset to every other read in the set. It was designed to speed de novo sequencing and assembly efforts in which an N ×N comparison of reads is necessary, and can also be used as a first step in read mapping for polymorphism detection.

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Fulcrum classification

Fulcrum specifications

Unique identifier:
OMICS_01049
Software type:
Package/Module
Restrictions to use:
None
Operating system:
Unix/Linux
Computer skills:
Advanced
Stability:
Stable
Maintained:
Yes
Alternative name:
Fulcrum Read Collapser
Interface:
Command line interface
Biological technology:
Illumina, Roche
Programming languages:
Python
Version:
043
Source code URL:
http://pringlelab.stanford.edu/project%20files/fulcrum_v_043.tar.gz

Fulcrum distribution

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No versioning.

Fulcrum support

Maintainer

  • Erik Lehnert <>

Credits

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Publications

Institution(s)

Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA

Funding source(s)

Supported by Gordon and Betty Moore Foundation (#2629), National Institutes of Health (5 T32 HG000044); National Science Foundation (Graduate Research Fellowship).

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