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TSTMP / Target Selection for human TransMembrane Proteins

Helps the target selection of human transmembrane proteins for structural genomics projects. TSTMP was built by sorting out proteins from the human transmembrane proteome with known structure and searching for suitable model structures for the remaining proteins by combining the results of a state-of-the-art transmembrane specific fold recognition algorithm and a sequence similarity search algorithm. The database serves as a guide to select those proteins, whose structures would have a great impact on the structural coverage of human transmembrane proteome.

Membranome / Membrane Proteome

Gathers information about bitopic proteins from six complete genomes (Homo sapiens, Arabidopsis thaliana, Dictyostelium discoideum, Saccharomyces cerevisiae, Escherichia coli and Methanocaldococcus jannaschii), corresponding to each kingdom. Membranome is a database which compiles 3D models of transmembrane (TM) domains, organized following a customized classification, for over 6000 bitopic proteins accompanied by their related structural and functional information.


Helps in understanding the relationship between amino acid sequences/structures and functions of membrane proteins. TMFunction is a collection of more than 2900 experimental data about important amino acid residues in membrane proteins, reported in the literature. This resource includes features to: (i) retrieve data for a particular protein and/or source, (ii) specify the type of the mutant as single, multiple and/or wild-type, (iii) select the function of the protein, (iv) mention the type of the protein, (v) extract data by authors, publication year and keywords, and (vi) download entire data.