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Associated diseases

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FunHunt specifications

Information


Unique identifier OMICS_17333
Name FunHunt
Interface Web user interface
Restrictions to use None
Input data The input to FunHunt are two possible orientations of a complex. Files representing the two starting conformations have to be in PDB format, specifically each file have to contain two chains with "TER" after each of them, and the occupancy column of the backbone atoms have to larger than 0.
Input format PDB
Computer skills Basic
Stability Stable
Maintained Yes

Maintainer


  • person_outline Ora Schueler-Furman <>

Publications for FunHunt

FunHunt in publications

 (2)
PMCID: 3519832
PMID: 23239984
DOI: 10.1371/journal.pone.0050769

[…] to this one could be used to train an artificial neural network or support vector machine classifier to pick native-like binding modes in a manner similar to that employed by nnscore, rf-score, and funhunt , , ., rosettaligand can sample and identify native-like binding modes when docking to comparative models. careful selection of templates and integration of biochemical data will increase […]

PMCID: 3039950
PMID: 21339984
DOI: 10.3390/ijms12010226

[…] the authors of rosetta warn about this problem, it is not uncommon for non-experienced users to rely heavily on the presence of any funnel as an indication of an accurate result., the program funhunt [,] attempts to distinguish between accurate and inaccurate funnels on the basis of several criteria such as, among others, the number of intermolecular contacts or the average conservation […]


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FunHunt institution(s)
Department of Molecular Genetics and Biotechnology, Hadassah Medical School, The Hebrew University, Jerusalem, Israel
FunHunt funding source(s)
This work was supported by The Israel Science Foundation founded by the Israel Academy of Science and Humanities, grant number 306/6.

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