A comprehensive and well-organized database of G-quadruplex ligands. G-quadruplexes are guanine-rich nucleic acid sequences in human telomeres and gene promoter regions. G4LDB currently contains >800 G-quadruplex ligands with 4000 activity records. It offers a user friendly interface that can meet a variety of data inquiries from researchers. For example, ligands can be searched for by name, molecular properties, structures, ligand activities and so on.
Beijing National Laboratory for Molecular Sciences (BNLMS), Center for Molecular Sciences, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China
G4LDB funding source(s)
Supported by National Natural Science Foundation of China [91027033, 81072576, 21205121 and 31200576]; Key Program of the Chinese Academy of Sciences [KJCX2-EW-N06-01].