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|Alternative name||Genes-to-Systems Breast Cancer|
|Restrictions to use||None|
- Homo sapiens
Publication for Genes-to-Systems Breast Cancer
Identifying miRNA sponge modules using biclustering and regulatory scores
[…] t al. , and the gene sets of these hallmark-associated GO terms are obtained from MsigDB v5.1 . The list of 2949 breast cancer genes are collected from COSMIC v77 , GAD , OMIM , BCGD  and G2SBC . The list of 428 breast cancer miRNAs are obtained by integrating five databases: HMDD v2.0 , miR2Disease , miRCancer , oncomiRDB  and phenomiR v2.0 .The experimentally validated mi […]
Managing, Analysing, and Integrating Big Data in Medical Bioinformatics: Open Problems and Future Perspectives
[…] of ontology-based data integration is closely tied to the consistency and expressivity of the ontology used in the integration process. Many resources exist that have ontology support: SNPranker , G2SBC , NSD , TMARepDB , Surface , and Cell cycle DB .A useful instrument for ontology exploration has been developed by the European Bioinformatics Institute (EBI), which allows easily visu […]
Using Expression Profiling to Understand the Effects of Chronic Cadmium Exposure on MCF 7 Breast Cancer Cells
[…] eviated lists of over- and under-expressed genes in cells chronically exposed to cadmium. Genes with known associations to breast cancer were identified using Genes-to-Systems Breast Cancer Database— G2SBC (http://www.itb.cnr.it/breastcancer/), which contains information about genes that have been previously reported in the literature to be associated with breast cancer. Furthermore, Gene Expressi […]
Impact of Cellular miRNAs on Circulating miRNA Biomarker Signatures
[…] one out of these four miRNAs to sex-specific tissue. Specifically we show that the strong female specific expresser: hsa-miR-940 to be detected in the cervix (). In addition through a search of the Genes-to-Systems Breast Cancer Database (http://www.itb.cnr.it/breastcancer/) we find evidence of interaction of all the 4 miRNAs with gene targets such as E2F1, E2F3, DAPK1 and others implicated to b […]
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