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G2SBC specifications


Unique identifier OMICS_03979
Name G2SBC
Alternative name Genes-to-Systems Breast Cancer
Restrictions to use None
Maintained No


  • Primates
    • Homo sapiens

Publication for Genes-to-Systems Breast Cancer

G2SBC citations


Identifying miRNA sponge modules using biclustering and regulatory scores

BMC Bioinformatics
PMCID: 5374547
PMID: 28361682
DOI: 10.1186/s12859-017-1467-5

[…] t al. [], and the gene sets of these hallmark-associated GO terms are obtained from MsigDB v5.1 []. The list of 2949 breast cancer genes are collected from COSMIC v77 [], GAD [], OMIM [], BCGD [] and G2SBC []. The list of 428 breast cancer miRNAs are obtained by integrating five databases: HMDD v2.0 [], miR2Disease [], miRCancer [], oncomiRDB [] and phenomiR v2.0 [].The experimentally validated mi […]


Managing, Analysing, and Integrating Big Data in Medical Bioinformatics: Open Problems and Future Perspectives

Biomed Res Int
PMCID: 4165507
PMID: 25254202
DOI: 10.1155/2014/134023

[…] of ontology-based data integration is closely tied to the consistency and expressivity of the ontology used in the integration process. Many resources exist that have ontology support: SNPranker [], G2SBC [], NSD [], TMARepDB [], Surface [], and Cell cycle DB [].A useful instrument for ontology exploration has been developed by the European Bioinformatics Institute (EBI), which allows easily visu […]


Using Expression Profiling to Understand the Effects of Chronic Cadmium Exposure on MCF 7 Breast Cancer Cells

PLoS One
PMCID: 3869932
PMID: 24376830
DOI: 10.1371/journal.pone.0084646

[…] eviated lists of over- and under-expressed genes in cells chronically exposed to cadmium. Genes with known associations to breast cancer were identified using Genes-to-Systems Breast Cancer Database— G2SBC (http://www.itb.cnr.it/breastcancer/), which contains information about genes that have been previously reported in the literature to be associated with breast cancer. Furthermore, Gene Expressi […]


Impact of Cellular miRNAs on Circulating miRNA Biomarker Signatures

PLoS One
PMCID: 3117799
PMID: 21698099
DOI: 10.1371/journal.pone.0020769

[…] one out of these four miRNAs to sex-specific tissue. Specifically we show that the strong female specific expresser: hsa-miR-940 to be detected in the cervix (). In addition through a search of the Genes-to-Systems Breast Cancer Database (http://www.itb.cnr.it/breastcancer/) we find evidence of interaction of all the 4 miRNAs with gene targets such as E2F1, E2F3, DAPK1 and others implicated to b […]


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G2SBC institution(s)
Institute for Biomedical Technologies, National Research Council, Segrate (Milan), Italy

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