An open-source, web platform that incorporates workflow technology and in-built access to bioinformatics resources including remote data warehouses and tools. Several public instances of Galaxy are available and it can be installed locally or in the cloud. These multiple installation options denote that Galaxy is able to accommodate varying user requirements, for example - data security, no IT experience, and no network transfer of data (depends on tools used). The Public Galaxy Toolshed is an appstore that hosts repositories containing Galaxy Tools, Galaxy Data Managers, custom Galaxy Datatypes, and exported Galaxy Workflows. The Toolshed supplies tools to Galaxy and provides tool developers with a framework and common repository for sharing, updating and managing tools.