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GANai specifications


Unique identifier OMICS_32790
Name GANai
Alternative name Generative Adversarial Network with Alternative Improvement
Software type Application/Script
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes


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Publication for Generative Adversarial Network with Alternative Improvement

GANai citations


Combinatorial In Silico Strategy towards Identifying Potential Hotspots during Inhibition of Structurally Identical HDAC1 and HDAC2 Enzymes for Effective Chemotherapy against Neurological Disorders

PMCID: 5684606
PMID: 29170627
DOI: 10.3389/fnmol.2017.00357

[…] erable role in unraveling the principal biochemical processes (Meng et al., ). Accurate structural modeling and correct prediction of activity are regarded as the two chief aims of molecular docking (Ganai, ). In order to gain insights on substantial ligand characteristics arising during the interaction between HDACs and their inhibitors, 5 HDACi from distinct structural groups were chosen (Supple […]


Within breed and multi breed GWAS on imputed whole genome sequence variants reveal candidate mutations affecting milk protein composition in dairy cattle

PMCID: 5604355
PMID: 28923017
DOI: 10.1186/s12711-017-0344-z

[…] h mutations were in complete LD and ranked 85th and 213rd, respectively, while in HOL, the two mutations ranked 48th and 109th, respectively (116th and 120th in multi-breed analysis). As suggested by Ganai et al. [], differences in β-LG content may be caused by different levels of expression of the A and B alleles rather than by the direct effect of amino-acid substitutions. Among the top 30 varia […]


Prospects of complete feed system in ruminant feeding: A review

PMCID: 5422247
PMID: 28507415
DOI: 10.14202/vetworld.2017.424-437

[…] t al. [] observed increase in in vitro DM degradability (IVDMD) and in vitro organic matter degradability (IVOMD) on supplementation of different herbs at 2% and 3% level in complete feeds for goats. Ganai et al. [] also reported that degradability of nutrients (DM, OM and neutral detergent fiber [NDF]), total gas production (TGP), total rumen nitrogen, and total volatile fatty acid (TVFA) concent […]


New Insights toward Colorectal Cancer Chemotherapy Using Natural Bioactive Compounds

Front Pharmacol
PMCID: 5348533
PMID: 28352231
DOI: 10.3389/fphar.2017.00109

[…] (Pampaloni et al., ), by suppressing the carcinogen induction of WNT/β-catenin signaling pathway (Zhang et al., ), by increasing the expression of antioxidant enzymes such as glutathione peroxidase (Ganai and Farooqi, ), and by preventing human CRC metastases due to MMP2 metalloproteases inhibition (Xiao et al., ). All these activities can be exploited by combinatory approaches in order to preven […]


Perspectives: using polymer modeling to understand the formation and function of nuclear compartments

PMCID: 5346151
PMID: 28091870
DOI: 10.1007/s10577-016-9548-2

[…] explicitly consider the coupling between chromatin structure and function have recently started to emerge (Barbieri et al. ; Brackley et al. ; Jerabek and Heermann ; Benedetti et al. ; Doyle et al. ; Ganai et al. ; Jost et al. ; Tark-Dame et al. ; Nazarov et al. ; Sanborn et al. ; Ulianov et al. ; Fudenberg et al. ; Tiana et al. ). In this perspective article, we are going to focus on some recent […]


Mechanistic Insights into the Binding of Class IIa HDAC Inhibitors toward Spinocerebellar Ataxia Type 2: A 3D QSAR and Pharmacophore Modeling Approach

Front Neurosci
PMCID: 5223442
PMID: 28119557
DOI: 10.3389/fnins.2016.00606

[…] rted HDACi allows researchers to analyze the chemical space occupied by HDAC's and to create filters that can be included in virtual screening experiments together with pharmacophores (Tang et al., ; Ganai et al., ; Zhou et al., ). […]


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GANai institution(s)
Institute for Biomedical Informatics, University of Kentucky, USA, Lexington, KY, USA; Department of Computer Science, University of Kentucky, Lexington, KY, USA; Department of Radiology, University of Kentucky, Lexington, KY, USA; Department of Internal Medicine, University of Kentucky, Lexington, KY, USA

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