GapFill pipeline

GapFill specifications


Unique identifier OMICS_13372
Name GapFill
Software type Package/Module
Interface Command line interface
Restrictions to use Academic or non-commercial use
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes


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  • person_outline Costas Maranas <>

Publication for GapFill

GapFill IN pipeline

PMCID: 3444828
PMID: 22997515
DOI: 10.1155/2012/323472

[…] incapable of a desired level of flux through the biomass reaction, have been previously proposed. gapfind [6] is a procedure that determines which metabolites in a network cannot be produced, and gapfill [6] determines a minimal set of reactions to add from a universal database so that a specified set of metabolites may be produced. these optimization-based procedures have already […]

GapFill institution(s)
Department of Industrial and Manufacturing Engineering, The Pennsylvania State University, University Park, PA, USA; Department of Chemical Engineering, The Pennsylvania State University, University Park, PA, USA
GapFill funding source(s)
This work was funded from the DOE grant (DE-FG03 01ER25499).

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