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GEC specifications

Information


Unique identifier OMICS_08747
Name GEC
Alternative name Genetic Engineering of living Cells
Software type Package/Module
Interface Command line interface, Graphical user interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes

Versioning


No version available

Maintainer


  • person_outline Andrew Phillips

Publication for Genetic Engineering of living Cells

GEC citations

 (3)
library_books

Computational Tools and Algorithms for Designing Customized Synthetic Genes

2014
Front Bioeng Biotechnol
PMCID: 4186344
PMID: 25340050
DOI: 10.3389/fbioe.2014.00041

[…] ure of DNA sequences. The genomic sequences that GenoCAD uses as biological parts are immutable, and no optimizations are applied in the creation of the constructs. Other circuit design tools include GEC (Pedersen and Phillips, ), TinkerCell (Chandran et al., ), and Clotho (Xia et al., ).In Section “,” we examine some of the most important objectives in synthetic gene design toward optimized expre […]

library_books

Towards the rational design of synthetic cells with prescribed population dynamics

2012
PMCID: 3479904
PMID: 22683525
DOI: 10.1098/rsif.2012.0280

[…] 0.0025 nM h−1) provided that was no less than 0.01 nM h−1. As expected, the oscillation period was considerably reduced when increasing the degradation rates with pH buffers (). Figure 4.We used the GEC software to impose conditions on kinetic rates associated with specific interactions, allowing us to assess conditions under which the desired behaviours are predicted to occur, and to specificall […]

library_books

Modeling Structure Function Relationships in Synthetic DNA Sequences using Attribute Grammars

2009
PLoS Comput Biol
PMCID: 2748682
PMID: 19816554
DOI: 10.1371/journal.pcbi.1000529

[…] of such semantic models in GenoCAD is the development of a data model allowing users to understand and possibly edit the functional model of the parts they use.A function description language called Genetic Engineering of living Cells (GEC) was recently introduced to specify the properties of a design . GEC is capable of finding a DNA sequence that implements the desirable phenotypic functions. S […]

Citations

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GEC institution(s)
Microsoft Research Cambridge, Cambridge, UK

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