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GPA | A single-gene perturbation repository for characterizing functional mechanisms of coding and non-coding genes


A database that includes a comprehensive collection of transcriptome profiles of protein coding genes, miRNAs and lncRNAs perturbed by knockdown or overexpression in human and mouse. GPA offers a wealth of information on differential expression patterns, comprehensive functional and pathway characterizations, enrichments of transcriptional factors and miRNAs, information flow in interaction network, and associations with cancers and drugs, together with extensive manually curated phenotype annotations.

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GPA classification

  • Animals
    • Homo sapiens
    • Mus musculus

GPA specifications

Unique identifier:
Restrictions to use:
Data access:
File download, Browse
Gene Perturbation Atlas
Community driven:
User data submission:
Not allowed

GPA support


  • Xia Li <>


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College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang, China; Key Laboratory of Cardiovascular Medicine Research, Harbin Medical University, Ministry of Education, Heilongjiang, China

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