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Exon-intron architecture comparison databases | Genome annotation

Intron positions upon the mRNA transcript are sometimes remarkably conserved even across distantly related eukaryotic species. This has made the comparison of intron–exon architectures across orthologous transcripts a very useful tool for studying various evolutionary processes. Moreover, the wide range of functions associated with introns may confer biological meaning to evolutionary changes in gene architectures.

Source text:
(Chorev et al., 2016) JuncDB: an exon-exon junction database. Nucleic Acids Res.

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