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GENE-TOX specifications

Information


Unique identifier OMICS_16475
Name GENE-TOX
Alternative name Genetic Toxicology Data Bank
Restrictions to use None
Community driven No
Data access Browse
User data submission Not allowed
Maintained Yes

Maintainer


  • person_outline Philip Wexler

Publication for Genetic Toxicology Data Bank

GENE-TOX citations

 (3)
library_books

Genome wide Regional Heritability Mapping Identifies a Locus Within the TOX2 Gene Associated With Major Depressive Disorder

2017
Biol Psychiatry
PMCID: 5553996
PMID: 28153336
DOI: 10.1016/j.biopsych.2016.12.012

[…] The significant haplotype block chr20:42555671–42579473 is located in the intron region and a proportion of an adjacent exon of gene TOX2. To investigate the potential functional effects from variants within this block, we imputed the nine genotyped SNPs within this block to 53 common SNPs based on Haplotype Reference Consorti […]

library_books

The Pan Genome of the Animal Pathogen Corynebacterium pseudotuberculosis Reveals Differences in Genome Plasticity between the Biovar ovis and equi Strains

2013
PLoS One
PMCID: 3544762
PMID: 23342011
DOI: 10.1371/journal.pone.0053818

[…] of deletions, especially in the biovar equi strains (). PiCp1, as previously described , harbors the pld gene and the fag operon and is present in all the strains. PiCp3 harbors the diphtheria toxin gene (tox) in C. pseudotuberculosis strain 31, and PiCps 7 and 15 harbor the spaD and spaA pilus gene clusters, respectively.To assess the level of plasticity in the PAIs, we used the orthologous data […]

library_books

Novel Corynebacterium diphtheriae in Domestic Cats

2010
PMCID: 3321947
PMID: 20350389
DOI: 10.3201/eid1604.091107

[…] incubation. Lack of toxin expression was corroborated by negative Vero cell assay results () and confirmed by using Western blot. Real-time PCR selective for the C. diphtheriae and C. ulcerans toxin gene (tox) () was positive for all feline isolates. However, real-time PCR for A and B subunits of tox () amplified subunit A but not subunit B. Sequence analysis of the tox gene was performed as prev […]

Citations

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GENE-TOX institution(s)
Toxicology and Environmental Health Information Program, National Institutes of Health, National Library of Medicine, Bethesda, MD, USA

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