Assists users in visualizing gene structure and annotated features. GSDS also processes coordinates for exons and coding DNA sequence (CDS) and supports conserved elements and binding sites. This software enables the customization of the shape, size and color of annotation features after their initial render via an integrated visual editor. User-specified phylogenetic tree can be added to the figure result to simplify the evolutionary analysis.
Produces images of one or more genes directly on the corresponding genomic locus. FancyGene is a web server that, starting from the genomic coordinates of one or more genes, generates a graphical representation of the corresponding gene structure. Users can change the resulting image by modifying colors and shapes and adding and/or removing objects and obtain images suitable for publications.
A web server for gene family to draw gene structure schematic diagrams. Users can submit genomic, CDS and transcript sequences. GSDraw uses this information to obtain the gene structure, protein motif and phylogenetics tree, then draw diagram for it. The genomic sequence, CDS sequence and transcription sequence of the same gene must use the same sequence ID in fasta file.
A web server for analysis and visualization of a comprehensive knowledge on mechanism-based disease connectivity. DiseaseConnect integrates comprehensive omics and literature data, including a large amount of gene expression data, genome-wide association studies catalog, and text-mined knowledge, to discover disease-disease connectivity via common molecular mechanisms. Moreover, the clinical comorbidity data and a comprehensive compilation of known drug-disease relationships are additionally utilized for advancing the understanding of the disease landscape and for facilitating the mechanism-based development of new drug treatments.
Estimates disease-disease correlations using protein interaction networks. DeCoaD Utilizes a disease-protein network to calculate the similarity or correlation between any two given diseases that have gene associations. It can display relationships between diseases, representing disease families that they belong to. This tool is useful for the discovery of novel links between diseases that call for experimental verifications.
Serves for visualization and statistical hypothesis testing of gene ontology (GO) category representation. eGOn is a tool that simplifies interpretation of GO annotation, and includes several functionalities: (1) visualization; (2) filtering; (3) statistical analysis; (4) connection to annotation database; and (5) export. These features assist users to assess the degree of similarity of GO category representation between different gene lists.
A standalone application for mapping gene structure information onto protein multiple sequence alignments. Based on the multiple sequence alignments the gene structures are aligned down to single nucleotides. GenePainter accounts for variable lengths in exons and introns, respects split codons at intron junctions and is able to handle sequencing and assembly errors, which are possible reasons for frame-shifts in exons and gaps in genome assemblies.