GeneMANIA specifications

Information


Unique identifier OMICS_02695
Name GeneMANIA
Interface Web user interface
Restrictions to use None
Input data Some genes.
Computer skills Basic
Stability Stable
Maintained Yes

Taxon


  • Animals
    • Caenorhabditis elegans
    • Danio rerio
    • Drosophila melanogaster
    • Homo sapiens
    • Mus musculus
    • Rattus norvegicus
  • Eubacteria
    • Escherichia coli
  • Fungi
    • Saccharomyces cerevisiae
  • Plants
    • Arabidopsis thaliana

Documentation


Maintainers


  • person_outline Quaid Morris <>
  • person_outline Gary Bader <>
  • person_outline Mohan Babu <>
  • person_outline GeneMANIA Team <>

Additional information


Desktop: http://apps.cytoscape.org/apps/genemania http://pages.genemania.org/help/

Information


Unique identifier OMICS_02695
Name GeneMANIA
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages Java, Javascript, Python, Shell (Bash)
Computer skills Advanced
Version 3.4.1
Stability Stable
Requirements Cytoscape
Maintained Yes

Taxon


  • Animals
    • Caenorhabditis elegans
    • Danio rerio
    • Drosophila melanogaster
    • Homo sapiens
    • Mus musculus
    • Rattus norvegicus
  • Eubacteria
    • Escherichia coli
  • Fungi
    • Saccharomyces cerevisiae
  • Plants
    • Arabidopsis thaliana

Download


Versioning


Add your version

Documentation


Maintainers


  • person_outline Quaid Morris <>
  • person_outline Gary Bader <>
  • person_outline Mohan Babu <>
  • person_outline GeneMANIA Team <>

Additional information


Desktop: http://apps.cytoscape.org/apps/genemania http://pages.genemania.org/help/

GeneMANIA articles

GeneMANIA citations

 (8)
2018
PMCID: 5920493

[…] of gbp genes in multiple normal tissues were determined with the gtex portal (http://www.gtexportal.org/home/, accessed april 25, 2017) (29). a gene function prediction website (genemania: http://genemania.org/, accessed march 15, 2017) (30) was also used to construct the gene-gene interaction networks. the database for annotation, visualization, and integrated discovery (david) v.6.7 […]

2018
PMCID: 5827688

[…] direction method14 to identify differentially expressed genes, and then up- and down-regulated gene sets were analyzed with enrichr6,7, l1000cds29, principal angle enrichment analysis (paea)15, and genemania5. another significant portion of the canned analyses currently contained within datasets2tools were generated by clustergrammer8 to visualize interactive heatmaps of rna-seq datasets […]

2018
PMCID: 5818516

[…] results will help to further validate the reliability and reproducibility of these eight prognostic genes and may aid in assessing the patients’ risk profile., we performed network analysis using genemania and cytoscape to identify the correlation among the eight genes identified from our expression analyses of genes with both high frequency cngs and consistent gene up-regulation. the derived […]

2018
PMCID: 5832109

[…] with the keyword “cancer/tumor,” allowing elimination of protein targets that were irrelevant to cancer. the remaining proteins were considered as candidate targets in subsequent analyses., the genemania server can generate hypotheses about gene function, analyze gene lists, and prioritize genes for functional assays [14]. after selection of homo sapiens as the organism, interesting genes […]

2017
PMCID: 5735898

[…] to better understand the reference genes, gene ontology classification using ncbi-david [15] was performed. to further understand the interaction between the reference genes, network analysis using genemania [16] and cytoscape [17] were performed., primer pairs were designed to amplify a specific gene product which resulted in a single peak in melt curve analysis, and the expected amplicon size […]

GeneMANIA institution(s)
Department of Biochemistry, University of Regina, Regina, SK, Canada; Banting and Best Department of Medical Research, Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, ON, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada; Department of Computer Science, University of Regina, Regina, SK, Canada; Department of Biochemistry, University of Toronto, Toronto, ON, Canada; Department of Biology, Carleton University, Ottawa, ON, Canada; Department of Computer Science, University of Toronto, Toronto, ON, Canada
GeneMANIA funding source(s)
Supported by grants from Global Leadership Round in Genomics and Life Sciences, by National Resource for Network Biology (P41 GM103504), Canadian Institutes of Health Research (CIHR), (MOP-130374), (MOP-82852), the National Sciences and Engineering Research Council of Canada, (DG-20234), a CIHR New Investigator award, a CIHR Vanier Graduate Scholarship and a Saskatchewan Postdoctoral Research Fellowship.

GeneMANIA reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review GeneMANIA