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GenePEN specifications

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Unique identifier OMICS_19338
Name GenePEN
Alternative name Gene Pairwise Elastic Net
Software type Application/Script
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages MATLAB
Computer skills Advanced
Stability Stable
Maintained Yes

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  • person_outline enrico.glaab <>

Publication for Gene Pairwise Elastic Net

GenePEN citation

library_books

Using prior knowledge from cellular pathways and molecular networks for diagnostic specimen classification

2015
PMCID: 4870394
PMID: 26141830
DOI: 10.1093/bib/bbv044

[…] et al. introduced a new instance of pen, which penalizes differences between the ‘absolute’ values of weights of interlinked features in a network graph. the motivation behind this approach, termed genepen, is that the magnitude of a weight in a linear model reflects the predictive value of the corresponding variable, so that the weights for irrelevant features are driven to zero […]


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GenePEN institution(s)
University of Luxembourg, Luxembourg Centre for Systems Biomedicine, Esch-sue-Alzette, Luxembourg; Adobe Research, Systems Technology Lab/Imagination Lab, San Jose, CA, USA

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