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GeneSpring GX specifications


Unique identifier OMICS_00853
Name GeneSpring GX
Alternative name Genespring
Software type Package/Module
Interface Graphical user interface
Restrictions to use License purchase required
Operating system Unix/Linux, Mac OS, Windows
License Commercial
Computer skills Medium
Stability Stable
Maintained Yes


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  • person_outline Spectrum Mill Team

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GeneSpring GX citations


Transcriptome Analysis of Circulating PBMCs to Understand Mechanism of High Altitude Adaptation in Native Cattle of Ladakh Region

Sci Rep
PMCID: 5955995
PMID: 29769561
DOI: 10.1038/s41598-018-25736-7

[…] the signal intensities were checked from the digit images using agilent feature extractor software version 9.5 (agilent technologies). the microarray raw data files in.txt format were imported to genespring gx 13.1 (agilent technologies) and subjected for quantile normalization which is highly effective in reducing variation between arrays. normalized data was analysed for statistically […]


Probiotic Lactobacillus fermentum strain JDFM216 stimulates the longevity and immune response of Caenorhabditis elegans through a nuclear hormone receptor

Sci Rep
PMCID: 5945636
PMID: 29748542
DOI: 10.1038/s41598-018-25333-8

[…] ensure that the change in gene expression was statistically significant and that false positives were <5%). functional annotations of genes from the gene ontology consortium were retrieved with genespring gx 7.3. genes were based on searches of david ( and medline ( databases., qrt-pcr was performed using the stepone™ real-time pcr […]


Defensive effect of microRNA 200b/c against amyloid beta peptide induced toxicity in Alzheimer's disease models

PLoS One
PMCID: 5940223
PMID: 29738527
DOI: 10.1371/journal.pone.0196929

[…] (agilent). the rna was hybridized to a mouse mirna release 16.0 8×60 k array (agilent) and a sureprint g3 mouse ge 8×60 k array (agilent), respectively, according to the manufacturer’s protocols. genespring gx (agilent) and ingenuity pathway analysis (ipa) software (ingenuity systems, redwood city, ca, usa) were employed to process the output data from the microarrays., according […]


Egr2 independent, Klf1 mediated induction of PD L1 in CD4+ T cells

Sci Rep
PMCID: 5935736
PMID: 29728568
DOI: 10.1038/s41598-018-25302-1

[…] access number e-mexp-1343 data. background adjustment and standardization were performed using bioconductor’s mas5 package in statistical software r. hierarchical clustering was performed in genespring gx (agilent technologies, santa clara, ca, usa) for genes whose expression was enhanced 1.5-fold compared to cd4+cd25−cd45rbhigh t cells (naïve cd4+ t cells), or expression decreased […]


The senescence associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1

Nat Commun
PMCID: 5928226
PMID: 29712904
DOI: 10.1038/s41467-018-04010-4

[…] scanned using the agilent dna microarray scanner (g2565ba), with data extracted with the agilent feature extraction software (v11.0.1.1). resulting single channel raw data were analyzed with agilent genespring gx software (v12.1). raw datasets were imported and log2-transformed according to the recommended default procedure and were subsequently quantile normalized. entities showing technical […]


MicroRNA expression profiling for the prediction of resistance to neoadjuvant radiochemotherapy in squamous cell carcinoma of the esophagus

J Transl Med
PMCID: 5918871
PMID: 29695253
DOI: 10.1186/s12967-018-1492-9

[…] was included for each run of real-time rt-pcr to ensure that the rna samples were not contaminated with genomic dna., for the microarray analysis, the software tools feature extraction and genespring gx 11.5 were used for quality control, statistical data analysis, mirna annotation and visualization. a detailed description of the statistical workup of the microarray data is given […]

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