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GeneSpring GX specifications


Unique identifier OMICS_00853
Name GeneSpring GX
Alternative name Genespring
Software type Package/Module
Interface Graphical user interface
Restrictions to use License purchase required
Operating system Unix/Linux, Mac OS, Windows
License Commercial
Computer skills Medium
Stability Stable
Maintained Yes


No version available



  • person_outline Spectrum Mill Team

Additional information

GeneSpring GX citations


Transcriptome Analysis of Circulating PBMCs to Understand Mechanism of High Altitude Adaptation in Native Cattle of Ladakh Region

Sci Rep
PMCID: 5955995
PMID: 29769561
DOI: 10.1038/s41598-018-25736-7
call_split See protocol

[…] ng. The signal intensities were checked from the digit images using Agilent Feature Extractor Software Version 9.5 (Agilent Technologies). The microarray raw data files in.txt format were imported to GeneSpring GX 13.1 (Agilent Technologies) and subjected for quantile normalization which is highly effective in reducing variation between arrays. Normalized data was analysed for statistically signif […]


Probiotic Lactobacillus fermentum strain JDFM216 stimulates the longevity and immune response of Caenorhabditis elegans through a nuclear hormone receptor

Sci Rep
PMCID: 5945636
PMID: 29748542
DOI: 10.1038/s41598-018-25333-8
call_split See protocol

[…] ents, Foster City, CA). The average fluorescence intensity for each spot was calculated, and local background was subtracted. All data normalization and selection of fold-changes were performed using GeneSpring 7.3.1 (Agilent Technology). Intensity-dependent normalization [locally weighted regression scatter plot smoothing (LOWESS)] was performed, wherein the ratio was reduced to the residual of t […]


Defensive effect of microRNA 200b/c against amyloid beta peptide induced toxicity in Alzheimer's disease models

PLoS One
PMCID: 5940223
PMID: 29738527
DOI: 10.1371/journal.pone.0196929

[…] Kit (Agilent). The RNA was hybridized to a Mouse miRNA Release 16.0 8×60 K array (Agilent) and a SurePrint G3 Mouse GE 8×60 K array (Agilent), respectively, according to the manufacturer’s protocols. GeneSpring GX (Agilent) and Ingenuity Pathway Analysis (IPA) software (Ingenuity Systems, Redwood City, CA, USA) were employed to process the output data from the microarrays. […]


The senescence associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1

Nat Commun
PMCID: 5928226
PMID: 29712904
DOI: 10.1038/s41467-018-04010-4

[…] scanned using the Agilent DNA microarray scanner (G2565BA), with data extracted with the Agilent Feature Extraction software (v11.0.1.1). Resulting single channel raw data were analyzed with Agilent GeneSpring GX software (v12.1). Raw datasets were imported and log2-transformed according to the recommended default procedure and were subsequently quantile normalized. Entities showing technical imp […]


MicroRNA expression profiling for the prediction of resistance to neoadjuvant radiochemotherapy in squamous cell carcinoma of the esophagus

J Transl Med
PMCID: 5918871
PMID: 29695253
DOI: 10.1186/s12967-018-1492-9
call_split See protocol

[…] For the microarray analysis, the software tools Feature Extraction and GeneSpring GX 11.5 were used for quality control, statistical data analysis, miRNA annotation and visualization. A detailed description of the statistical workup of the microarray data is given as Add […]


Transcriptome profiling of Brassica napus stem sections in relation to differences in lignin content

BMC Genomics
PMCID: 5903004
PMID: 29661131
DOI: 10.1186/s12864-018-4645-6
call_split See protocol

[…] erred to ArrayPro Analyzer software (Media Cybernetics Inc., Bethesda, MD, USA) for image analysis, spot verification, normalization, filtering and feature extractions. A standard statistical program GeneSpring GX (Agilent Technologies, Santa Clara, CA, USA) was used to determine that the data set would fit a normal distribution (log 10) and to check the validity of expression data by assessing th […]


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GeneSpring GX institution(s)
Agilent, Santa Clara, CA, USA

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