GeneWanderer statistics

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Citations per year

Number of citations per year for the bioinformatics software tool GeneWanderer
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Tool usage distribution map

This map represents all the scientific publications referring to GeneWanderer per scientific context
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Associated diseases

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GeneWanderer specifications

Information


Unique identifier OMICS_07803
Name GeneWanderer
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability No
Maintained No

Taxon


  • Primates
    • Homo sapiens

Versioning


No version available

Publication for GeneWanderer

GeneWanderer citations

 (12)
library_books

Dysfunction of Myosin Light‐Chain 4 (MYL4) Leads to Heritable Atrial Cardiomyopathy With Electrical, Contractile, and Structural Components: Evidence From Genetically‐Engineered Rats

2017
PMCID: 5721782
PMID: 29080865
DOI: 10.1161/JAHA.117.007030

[…] is in 17q21 provided a maximal logarithm of the odds score of 5.3 (Figure A). Haplotype analysis showed a ≈6 Mbp (or ≈5 cM) region exclusively shared by patients.Based on bioinformatic analysis, both GeneWanderer and Endeavour ranked MYL4 in the top 2 genes in terms of its functional relationship to SCN5A and GJA5 (listed in Tables and ). Importantly, the identified missense mutation c. 31G>A in […]

library_books

Recent Advances and Emerging Applications in Text and Data Mining for Biomedical Discovery

2015
Brief Bioinform
PMCID: 4719073
PMID: 26420781
DOI: 10.1093/bib/bbv087

[…] rther validation are critically needed, and method development in this area would greatly facilitate discovery.Many gene prioritization algorithms have been developed to address this problem, such as GeneWanderer [], GeneSeeker [], GeneProspector [], SUSPECTS [], G2D [] and Endeavour [], among others [, ]. A comparative review of these methods can be found in Tranchevent et al. []. The general pre […]

library_books

A computational framework for the prioritization of disease gene candidates

2015
BMC Genomics
PMCID: 4547404
PMID: 26330267
DOI: 10.1186/1471-2164-16-S9-S2

[…] modeling of networks have aided our understanding of how biological networks operate. A number of computational approaches to prioritize candidate genes have been proposed including: ToppGene [] and GeneWanderer [] which rank candidate genes based on known associations with disease genes using diverse data sources and methodology. The study by Vanunu et al. [] applied a diffusion- based method na […]

library_books

Genomic convergence and network analysis approach to identify candidate genes in Alzheimer's disease

2014
BMC Genomics
PMCID: 4028079
PMID: 24628925
DOI: 10.1186/1471-2164-15-199

[…] p value <0.05 linked to AD were selected for further analysis. The chromosomal coordinates for each linkage region were retrieved using UCSC genome browser. These were then used to extract genes from GeneWanderer web server [] which provides a method for prioritization of candidate genes by using four different ranking strategies (random walk, diffusion kernel, shortest path and direct interaction […]

library_books

Approaches for Recognizing Disease Genes Based on Network

2014
Biomed Res Int
PMCID: 3953674
PMID: 24707485
DOI: 10.1155/2014/416323

[…] fter many iterations, steady-state P ∞ is denoted as P ∞ = [(1 − η)u ∞  ηv ∞]T. In this way, the steady probabilities u ∞ and v ∞ are used to rank the genes and disease phenotypes. A web server named GeneWanderer, which is a computational method that prioritizes a set of candidate genes according to their probability to become involved in a particular disease or phenotype using HWRH or diffusion k […]

library_books

Candidate gene association studies: a comprehensive guide to useful in silico tools

2013
BMC Genet
PMCID: 3655892
PMID: 23656885
DOI: 10.1186/1471-2156-14-39

[…] n covered in detail elsewhere []. The hosted web portal – Gene Prioritization Portal (http://www.esat.kuleuven.be/gpp), links out to 33 current computational tools for this purpose, such as GeneRank, GeneWanderer, Caesar, SNPs3D and GeneDistiller among many others. This resource compares many online computational tools and thus, provides an efficient and comprehensive guide to help the user develo […]


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GeneWanderer institution(s)
Institute for Medical Genetics, Charité Universitätsmedizin Berlin, Berlin, Germany
GeneWanderer funding source(s)
Supported by the Berlin-Brandenburg Center for Regenerative Therapies (BCRT) (Bundesministerium fur Bildung und Forschung, project number 0313911) and the Deutsche Forschungsgemeinschaft (SFB 760).

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