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GeneWanderer specifications


Unique identifier OMICS_07803
Name GeneWanderer
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability No
Maintained No


  • Primates
    • Homo sapiens


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Publication for GeneWanderer

GeneWanderer citations


Recent Advances and Emerging Applications in Text and Data Mining for Biomedical Discovery

Brief Bioinform
PMCID: 4719073
PMID: 26420781
DOI: 10.1093/bib/bbv087

[…] validation are critically needed, and method development in this area would greatly facilitate discovery., many gene prioritization algorithms have been developed to address this problem, such as genewanderer [], geneseeker [], geneprospector [], suspects [], g2d [] and endeavour [], among others [, ]. a comparative review of these methods can be found in tranchevent et al. []. the general […]


A computational framework for the prioritization of disease gene candidates

BMC Genomics
PMCID: 4547404
PMID: 26330267
DOI: 10.1186/1471-2164-16-S9-S2

[…] modeling of networks have aided our understanding of how biological networks operate. a number of computational approaches to prioritize candidate genes have been proposed including: toppgene [] and genewanderer [] which rank candidate genes based on known associations with disease genes using diverse data sources and methodology. the study by vanunu et al. [] applied a diffusion- based method […]


Identification of highly related references about gene disease association

BMC Bioinformatics
PMCID: 4162969
PMID: 25155502
DOI: 10.1186/1471-2105-15-286

[…] employed by the prediction techniques included chromosomal locations of the candidate genes [], anatomical ontology [], gene ontology [], protein-protein interaction networks (e.g., employed by the genewanderer systemh), indirect but related evidence about a gene g and a disease d reported in the literature [], overlap of the index terms of references related to g and d [], co-occurrence […]


Genomic convergence and network analysis approach to identify candidate genes in Alzheimer's disease

BMC Genomics
PMCID: 4028079
PMID: 24628925
DOI: 10.1186/1471-2164-15-199

[…] model-free arp linkage analysis approach. a total of 2976 genes were retrieved using ucsc genome browser [] from these linkage regions and genes were ranked according to their score obtained from genewanderer web server []., further, for the gwa dataset, 19,532 single nucleotide polymorphisms (snps) with p value <0.0001 [] were selected. these snps were mapped to their corresponding genes […]


Approaches for Recognizing Disease Genes Based on Network

Biomed Res Int
PMCID: 3953674
PMID: 24707485
DOI: 10.1155/2014/416323

[…] many iterations, steady-state p ∞ is denoted as p ∞ = [(1 − η)u ∞  ηv ∞]t. in this way, the steady probabilities u ∞ and v ∞ are used to rank the genes and disease phenotypes. a web server named genewanderer, which is a computational method that prioritizes a set of candidate genes according to their probability to become involved in a particular disease or phenotype using hwrh or diffusion […]


Improving Disease Gene Prioritization by Comparing the Semantic Similarity of Phenotypes in Mice with Those of Human Diseases

PLoS One
PMCID: 3375301
PMID: 22719993
DOI: 10.1371/journal.pone.0038937

[…] genes of disease ., several methods have been developed to prioritize candidate genes for diseases using a variety of data, primarily relying on known gene–disease associations . for example, the genewanderer approach employs a distance measure on a protein-protein interaction network to identify gene–disease associations. another system, endeavour , utilizes a set of known genes to create […]

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GeneWanderer institution(s)
Institute for Medical Genetics, Charité Universitätsmedizin Berlin, Berlin, Germany
GeneWanderer funding source(s)
Supported by the Berlin-Brandenburg Center for Regenerative Therapies (BCRT) (Bundesministerium fur Bildung und Forschung, project number 0313911) and the Deutsche Forschungsgemeinschaft (SFB 760).

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