Genome editing software tools and databases

Programmable nucleases - including zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and RNA-guided engineered nucleases (RGENs) derived from the bacterial clustered regularly interspaced short palindromic repeat (CRISPR)-Cas…

Genome editing steps

Bioinformatics tools

Biological databases

Most recent bioinformatics tools

pgRNAFinder
Web

pgRNAFinder

Provides eight vertebrate genomes for guide RNA (gRNA) design. pgRNAFinder…

Provides eight vertebrate genomes for guide RNA (gRNA) design. pgRNAFinder contains three different modules: (1) a single gRNA design module, (2) a short distance paired-gRNA design module and (3) a…

CRISPy-web
Web

CRISPy-web

Designs single-guide (sgRNA) for any gene/region of interest in user-submitted…

Designs single-guide (sgRNA) for any gene/region of interest in user-submitted genome data. CRISPy-web is implemented as a standalone web application for Cas9 target prediction. It consists of…

CRISPRpred
Desktop

CRISPRpred

Permits users to predict on-target activity of in-silico sgRNAs efficiently…

Permits users to predict on-target activity of in-silico sgRNAs efficiently based on the applications of Support Vector Machine (SVM) model. This tool provides two key factors that improve the…

predictSGRNA
Desktop

predictSGRNA

Enables to predict single guide RNA (sgRNA) target sequences efficiency.…

Enables to predict single guide RNA (sgRNA) target sequences efficiency. PredictSGRNA implements an algorithm based on position-dependent dinucleotide model. This tool is an R package implementing…

Curators for Genome editing

  • Mikhail Zaslavskiy's avatar image
    Mikhail Zaslavskiy
    Consultant, Paris, France

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