Genome editing steps

Bioinformatics tools

Biological databases

Programmable nucleases – including zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and RNA-guided engineered nucleases (RGENs) derived from the bacterial clustered regularly interspaced short palindromic repeat (CRISPR)-Cas…

Genome editing software tools and databases

Most Recent Tools

Guide Picker
Web

Guide Picker

Allows side-by-side correlative analysis of scoring functions. The CRISPR Guide…

Allows side-by-side correlative analysis of scoring functions. The CRISPR Guide Picker mode is an addition to the DESKGEN Cloud Platform. It allows user to visualize data from four sgRNA design…

ZiF-Predict
Web

ZiF-Predict

Predicts recognition helices for C2H2 zinc fingers that bind to specific target…

Predicts recognition helices for C2H2 zinc fingers that bind to specific target DNA sites. ZiF-Predict is based on artificial neural network using an exhaustive dataset of zinc finger proteins (ZFP)…

ZifNN
Web

ZifNN

Predicts high throughput of optimal zinc finger protein for 9 bp DNA sequences…

Predicts high throughput of optimal zinc finger protein for 9 bp DNA sequences of choice. ZifNN is inspired from an ensemble machine learning approach, and incorporates the predictions made by 100…

GuideScan
Desktop
Web

GuideScan

Allows for the design of CRISPR guide RNA libraries that can be used to edit…

Allows for the design of CRISPR guide RNA libraries that can be used to edit coding and noncoding genomic regions. GuideScan produces high-density sets of guide RNAs (gRNAs) for single- and…

Curators for Genome editing

  • Mikhail Zaslavskiy's avatar image
    Mikhail Zaslavskiy
    Consultant, Paris, France

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