A web server for evaluating the performance of genome assemblers. GenomeABC can be used to evaluate the performance of assemblers on real, hypothetical and mutate genomes. (a) Whole genome is shattered into short reads by sequencers, (b) assemblers read these short reads, (c) assemblers reassembled short reads to generate genome/contigs, (d) performance of an assembler is measured by comparing reference/original with assembled genome, (e) performance of assemblers is calculated in term of N50, error rate and coverage.