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Genomic Analysis of Mutations Extracted by Sequencing GAMES

A pipeline aiming to serve as an efficient middleman between data deluge and investigators. GAMES attains multiple levels of filtering and annotation, such as aligning the reads to a reference genome, performing quality control and mutational analysis, integrating results with genome annotations and sorting each mismatch/deletion according to a range of parameters. Variations are matched to known polymorphisms. The prediction of functional mutations is achieved by using different approaches. Overall GAMES enables an effective complexity reduction in large-scale DNA-sequencing projects.

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GAMES classification

GAMES specifications

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Academic or non-commercial use
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Command line interface
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DAMA, Data Mining for Analysis of DNA, Department of Morphology and Embryology and TecnoPolo for Life Sciences, University of Ferrara, Ferrara, Italy

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