- Unique identifier:
- Web user interface
- Input data:
- Genomic coordinates, dbSNP id, protein position, gene symbol, protein name
- Programming languages:
- Genomic position mapping to 3D data
- Restrictions to use:
- Output data:
- Protein coordinates, protein structures, pathogenic variants, functional sites, polymorphism sites, modeling of the mutant structure, analysis of intra-protein contacts, instant access to functional predictions and predictions of thermo-stability changes
- Computer skills:
- Homo sapiens
- Oz Solomon <>
No open topic.
(Solomon et al., 2016)
G23D: Online tool for mapping and visualization of genomic variants on 3D protein structures.
PMID: 27565432 DOI: 10.1186/s12864-016-3028-0
Cancer Research Center, Sheba Medical Center, Ramat-Gan, Israel; The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel; Pediatric Immunology Service, Jeffrey Modell Foundation, Sheba Medical Center, Ramat-Gan, Israel; Edmond and Lily Safra Children’s Hospital, Sheba Medical Center, Ramat-Gan, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
The work was supported by grants from the Varda and Boaz Dotan Research Center in Hemato-oncology affiliated with the CBRC of Tel Aviv, University Flight Attendant Medical Research Institute (FAMRI), Israeli Centers of Excellence (I-CORE) Program (ISF grants no. 41/11 and no. 1796/12).
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