Bioinformatics tools for genomics

Genomics is an interdisciplinary field of molecular biology focusing on the DNA content of living organisms. Genomics techniques are mainly focused on DNA sequencing, DNA structure analysis, genome editing, population genomics, DNA-protein interactions, phylogenomics, or synthetic biology. High-throughput DNA sequencing technologies and bioinformatics have transformed genome analysis by mapping and decrypting coding and non-coding DNA sequences, their evolution and inter-relationships. Software tools and databases are proposed here for genome annotation, phylogenomics studies, comparative genomics, genome editing, genome variant and DNA structure analysis, personal and population genomics, as well as epigenomic modifications which include DNA methylation, histone modifications and nucleosome positioning. The understanding of genomic data is opening many opportunities for health and medical research, such as personalized medicine and biomarkers discovery for diagnosis and treatment of cancer and numerous diseases. 

DNA sequence

DNA structure

Genome editing

Population genomics

DNA-Protein interactions

Phylogenetics

Synthetic biology

Low-level DNA detection

Text mining