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- person_outline Karsten Borgwardt
Publication for GLIDE
gammaMAXT: a fast multiple testing correction algorithm
[…] Among the numerous software designed for pair-wise or higher-order SNP-SNP interactions, we recall BOOST , BiForce , epiGPU , EpiBlaster , GLIDE , Multifactor Dimensionality Reduction (MDR) [, ] and Model-Based Multifactor Dimensionality Reduction (MB-MDR) [, ]. The following comparison of these approaches is mainly inspired from  wh […]
The Challenges of Genome Wide Interaction Studies: Lessons to Learn from the Analysis of HDL Blood Levels
[…] .r-project.org/web/packages/coxme/) and adjusted for PCs. In the discovery and filtering stage, the HDL levels after adjustment for sex and age were normalised around zero as this is a requirement of GLIDE. To compare the βint in the discovery and filtering stage with the ßint in the replication stage, we also calculated the βint in the Rotterdam Study cohorts without scaling around zero for the m […]
Discovering epistasis in large scale genetic association studies by exploiting graphics cards
[…] Upon searching the literature for epistasis detection methods on GPUs, we were able to locate and download programs for eight published methods, which we list as EpiGPU(Hemani et al., ), GLIDE (Kam-Thong et al., ), GBOOST(Yung et al., ), cuGWAM(Kwon et al., ), EPIBLASTER(Kam-Thong et al., ), EpiGPUHSIC(Kam-Thong et al., ), SHEsisEpi(Hu et al., ), and MDRGPU(Greene et al., ). We evalua […]
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