GlobalFit

[…] at a single dominant binding site occurs for each ligand. An excellent protocol on how to organize CD experiments and data processing is given in reference []. One of the intriguing new approaches is GlobalFit processing [–], whereby the data from all titration experiments (e.g., CD, fluorescence, ITC, etc.), done at approximately similar conditions (concentration range, buffer), are processed sim […]

[…] For each network with EGCs, we then used a slightly modified version of GlobalFit [] to suggest a minimal number of reaction removals that eliminate all EGCs, allowing independent removals of forward and backward directions for reversible reactions. GlobalFit was original […]

[…] utions, instead of finding solutions to solve the inconsistencies case by case. This is the approach that is also considered in very recent study of Hartleb et al.. In this study, the authors present GlobalFit, a bi-leveloptimization method, which identifies minimal set of model changes to achieve a model that can correctly predict all of the experimental data of growth and non-growth cases.Here, […]

[…] of the resulting edge was measured. At least six points were measured and averaged. XRR was performed by using a Rigaku Smartlab X-ray diffractometer, and the reflection patterns were fitted by using GlobalFit software (Rigaku). Monochromatized Cu Kα radiation (λ = 0.154 nm) was generated at 45 kV and 200 mA. To conduct XRR measurements of the interlayers, the samples were prepared by using the fl […]

[…] ere equivalent between the two anomers of each diastereomer, thus halving the total number of possible parameter combinations. The final strategy, targeting all conformers in one fitting run (called “Globalfit”) and enforcing equivalency among alcohol groups in the ring to avoid overfitting, yielded a single parameter set that was chosen as the final parameter set for both of the carbohydrate seri […]

[…] s, two samples, x=60 and x=5, were characterized by X-ray reflectivity. reports the two reflectivity curves with related fits. The fits were performed with the Integrated Thin Film Analysis Software GlobalFit 1.3 (Rigaku Corporation). The background was not measured, but was included as a fitting parameter. The main purpose of this analysis was to extrapolate the thickness of the film and the den […]