GlobalFit

[…] a single dominant binding site occurs for each ligand. an excellent protocol on how to organize cd experiments and data processing is given in reference []. one of the intriguing new approaches is globalfit processing [–], whereby the data from all titration experiments (e.g., cd, fluorescence, itc, etc.), done at approximately similar conditions (concentration range, buffer), are processed […]

[…] instead of finding solutions to solve the inconsistencies case by case. this is the approach that is also considered in very recent study of hartleb et al.. in this study, the authors present globalfit, a bi-leveloptimization method, which identifies minimal set of model changes to achieve a model that can correctly predict all of the experimental data of growth and non-growth cases., […]

[…] the resulting edge was measured. at least six points were measured and averaged. xrr was performed by using a rigaku smartlab x-ray diffractometer, and the reflection patterns were fitted by using globalfit software (rigaku). monochromatized cu kα radiation (λ = 0.154 nm) was generated at 45 kv and 200 ma. to conduct xrr measurements of the interlayers, the samples were prepared by using […]

[…] two samples, x=60 and x=5, were characterized by x-ray reflectivity. reports the two reflectivity curves with related fits. the fits were performed with the integrated thin film analysis software globalfit 1.3 (rigaku corporation). the background was not measured, but was included as a fitting parameter. the main purpose of this analysis was to extrapolate the thickness of the film […]

[…] anomerfit, was to constrain the terms for the two anomers for each diastereomer to be identical, yielding 8 sets of alpha and thole terms. the third strategy consisted of one single mcsa run, termed globalfit, thereby yielding a single set of alpha and thole terms, as well as the previously determined partial atomic charges, for all 16 diastereomers. the error function defined during the mcsa […]