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globaltest | A global test for groups of genes: testing association with a clinical outcome

Allows researchers to use prior information on groupings of genes and to specifically investigate groups of genes that interest them from a biological point of view. When researchers have many candidate pathways, available e.g. from gene ontology databases or programs, the global test can be used to find promising pathways. Special attention is given to visualizations of the test result, focusing on the associations between samples and showing the impact of individual genes on the test result. Glotest Special include graphs to search for outlying samples and diagnostic plots to judge how much each individual gene contributes to a significant test result for the group.

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globaltest classification

globaltest specifications

Unique identifier:
OMICS_02084
Interface:
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
License:
GNU General Public License version 2.0
Stability:
Stable
Software type:
Package/Module
Restrictions to use:
None
Programming languages:
R
Computer skills:
Advanced
Maintained:
Yes

globaltest distribution

versioning

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globaltest support

Documentation

Credits

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Publications

Institution(s)

Department of Medical Statistics, Leiden University Medical Center, Leiden, Netherlands; Mathematical Institute, Leiden University, Netherlands; Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, Netherlands

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