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Lysine glycation site detection software tools | Post-translational modification data analysis

Lysine glycation site detection software tools | Post-translational modification data analysis

Similar to the regular enzymatic glycosylation, glycation also attaches a sugar molecule to a peptide, but does not need the help of an enzyme. Glycation may occur both inside and outside the host body, and will compete with the glycosylation procedure for functional regulation of mature protein products. The glycated residues do not show significant patterns, which make both in silico sequence-level predictors and wet-lab validations a major challenge.

Source text:
(Xu et al., 2017) Gly-PseAAC: Identifying protein lysine glycation through sequences. Gene.

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