Identifies glycosylation relevance in gut barrier in response to commensal and pathogenic bacteria for modulating the gut immune tolerance. The GlycoGAIT is a web database whose interface enables the users to quickly compare or interpret changes in expression patterns of glycome genomics below different gut associated inflammatory conditions. This tool delivers informations for glycogene expression analysis under inflammatory disease conditions. It brings also the gene set of glycogenes along with lectins along with publically available gene expression data obtained from human gastric biopsy samples with dysregulated immune function that aids in the systematic analysis of the gene expression changes in disease conditions at the transcriptome level.
Connexios Life Sciences, Prestige South End, Basavanagudi, Bangalore, Karnataka, India; Glycoscience Group, National Centre for Biomedical Engineering Science, National University of Ireland Galway, Galway, Ireland
GlycoGAIT funding source(s)
This work was supported by the Science Foundation Ireland Strategic Research Cluster (SRC) programme to Alimentary Glycoscience Research Cluster (grant 08/SRC/B1393), and the European Union FP7 programme in support of the GlycoHIT project (grant 260600).