GMDR pipeline

GMDR specifications


Unique identifier OMICS_24673
Alternative name Generalized Multifactor Dimensionality Reduction
Software type Application/Script
Interface Command line interface, Graphical user interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages Java, Perl
License GNU General Public License version 2.0
Computer skills Advanced
Version 0.9
Stability Beta
Requirements Java SE Runtime Environment
Maintained Yes



Add your version



  • person_outline Xiang-Yang Lou <>
  • person_outline Guo-Bo Chen <>

Publications for Generalized Multifactor Dimensionality Reduction

GMDR citations

PMCID: 5706800

[…] prediction accuracy as a benchmark based on 1,000 shuffles. in order to correct for multiple testing, we applied a conservative bonferroni correction factor for the number of tests employed in the gmdr analysis., based on the effect sizes in this study, the power to detect significant associations was evaluated by quanto software ( the manhattan and q-q […]

PMCID: 4178067

[…] bivariate analysis had higher test accuracy and cross validation consistency under the correct analytical model, for example, the means of test accuracy and cross validation consistency with gee-gmdr are 0.665 and 10.000 for digenic model, 0.630 and 9.940 for trigenic model, 0.587 and 8.580 for tetragenic model, respectively, whereas those with gmdr for trait 1 (trait 2) are 0.617 (0.618) […]

GMDR institution(s)
Institute of Bioinformatics and Institute of Crop Science, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, China; Research Center for Air Pollution and Health, Zhejiang University, Hangzhou, China; Institute of Computer Application Technology, College of Computer Science and Technology, Zhejiang University of Technology, Hangzhou, China; Queensland Brain Institute, University of Queensland, St Lucia, QLD, Australia; Sir Run Run Shaw Hospital and Institute of Translational Medicine, School of Medicine, Zhejiang University, Hangzhou, China; Department of Biostatistics and Bioinformatics, Tulane University, New Orleans, LA, USA
GMDR funding source(s)
Supported in part by National Institute of Health Grant R01 DA025095 and National Science Foundation DMS1462990, the National Basic Research Programs of China (973 Programs) 2011CB109306, and the National Natural Science Foundation 31271608 and 31470083.

GMDR reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review GMDR