GMDR

[…] interactions (ggis) are a known cause of missing heritability. multifactor dimensionality reduction (mdr) is one of most commonly used methods for ggi detection. the generalized multifactor dimensionality reduction (gmdr) method is an extension of mdr method that is applicable to various types of traits, and allows covariate adjustments. our previous fuzzy mdr […]

[…] adjusted for same covariates under the additive model., to estimate the epistatic contribution of variants in six nachr subunit genes to nd, we performed snp-by-snp interaction analysis using the gmdr-gpu program developed by our group,, performing an exhaustive search of all combinations containing 2–5 snps each. the best interaction model was determined according to the following three […]

[…] of ultrasound, the patients were stratified into three groups: non-plaque group, vulnerable plaque (vp) group and stable plaque (sp) group. furthermore, gene-gene interactions were analyzed using generalized multifactor dimensionality reduction (gmdr) methods., the rs1131882, rs2317676, and rs16863323 three-loci interactions may confer a higher risk of carotid plaque vulnerability, and might […]

[…] g × e interaction, psychiatric interviews, self-report questionnaires for cht, and genotyping for bdnf val66met were carried out on 201 schizophrenic patients. g × e interactions were analyzed by generalized multifactor dimensionality reduction (gmdr)., among all patients, 11.9%, 19.4%, 23.4%, 26.4%, and 73.6% reported emotional abuses, physical abuses (pa), sexual abuses (sa), emotional […]

[…] score below 0.9) and preeclampsia was also calculated by logistic regression in snpstat software. the results of the logistic regression were presented as ors and 95% ci and p values., moreover, the generalized multifactor dimensionality reduction (gmdr, v0.9; http://www.ssg.uab.edu/gmdr/) [, ] analysis was used to calculate the interaction among five studied polymorphisms (−1607 1g/2g mmp1 […]