GOLEM specifications


Unique identifier OMICS_18771
Alternative name Gene Ontology Local Exploration Map
Software type Application/Script
Interface Graphical user interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages Java
Computer skills Medium
Maintained Yes


No version available


  • person_outline Olga G. Troyanskaya
  • person_outline Rachel Sealfon
  • person_outline Matthew Hibbs
  • person_outline Curtis Huttenhower
  • person_outline Chad L Myers

Publication for Gene Ontology Local Exploration Map

GOLEM citations


High hydrostatic pressure adaptive strategies in an obligate piezophile Pyrococcus yayanosii

Sci Rep
PMCID: 4890121
PMID: 27250364
DOI: 10.1038/srep27289

[…] pC software) were determined, over-expressed KEGG categories were identified using the KOBAS website and a binomial test. Over-represented GO terms were identified using the GO Local Exploration Map (GOLEM) software with a FDR of 5%. The Enrichment Map plugin of the Cytoscape software was used to summarize the data. Syntheny of the regulated gene clusters was represented using the SyntTax software […]


Cellular Robustness Conferred by Genetic Crosstalk Underlies Resistance against Chemotherapeutic Drug Doxorubicin in Fission Yeast

PLoS One
PMCID: 3554685
PMID: 23365689
DOI: 10.1371/journal.pone.0055041

[…] Next we used Gene Ontology Local Exploration Map (GOLEM) (http://go.princeton.edu/cgi-bin/GOTermFinder) to classify the DXR genes into different functional categories. At a statistical confidence of p<0.01, GOLEM […]

GOLEM institution(s)
Department of Computer Science, Princeton University, Princeton, NJ, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Carl Icahn Labs, Princeton, NJ, USA
GOLEM funding source(s)
Supported by the SPE program, NSF grant DGE-9972930, the Quantitative and Computational Biology Program NIH grant T32 HG003284, an Alfred P. Sloan Research Fellow, NIH grant R01 GM071966 and NSF grant IIS-0513552 and NIGMS Center of Excellence grant P50 GM071508.

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