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GOrilla specifications


Unique identifier OMICS_02282
Name GOrilla
Alternative name Gene Ontology enRIchment anaLysis and visuaLizAtion tool
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publication for Gene Ontology enRIchment anaLysis and visuaLizAtion tool

GOrilla citations


Aurora kinase A (AURKA) interaction with Wnt and Ras MAPK signalling pathways in colorectal cancer

Sci Rep
PMCID: 5951826
PMID: 29760449
DOI: 10.1038/s41598-018-24982-z

[…] ter than 1.5 or less than −1.5. The significantly deregulated genes are available in Supplementary Table  for SW480 and Supplementary Table  for Caco2. GO enrichment analysis was performed using the ‘Gene Ontology enRIchment anaLysis and visuaLizAtion tool’ (http://cbl-gorilla.cs.technion.ac.il/). […]


Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development

Genome Med
PMCID: 5899322
PMID: 29653584
DOI: 10.1186/s13073-018-0534-5

[…] e test correction method (BH-corrected p value < 0.05). Only expressed transcription factors were considered for the analysis (raw read count > 3). Gene Ontology (GO) analysis was performed using the GOrilla (gene ontology enrichment analysis and visualization) tool []. GO terms with false discovery rate (FDR) < 0.05 were considered significantly altered. All RNA-Seq data have been uploaded to the […]


De novo draft assembly of the Botrylloides leachii genome provides further insight into tunicate evolution

Sci Rep
PMCID: 5882950
PMID: 29615780
DOI: 10.1038/s41598-018-23749-w

[…] (groups of clustered genes), Clustal-Omega (multiple sequence alignments), EMBOSS (consensus sequences) and BLASTp (top hit) are provided in File .The overrepresentation analysis was performed using GOrilla with Homo sapiens as the organism background, using a p-value threshold of 10−3 and REVIGO TreeMap (similarity factor “medium” of 0.7) for visualization. Results are provided in File . […]


Extensive and systematic rewiring of histone post translational modifications in cancer model systems

Nucleic Acids Res
PMCID: 5934616
PMID: 29618087
DOI: 10.1093/nar/gky224

[…] rted in Dataset S3.GO analysis of the proteins significantly changing in the comparison between short-term cultures and tissue, or long-term cultures and short-term cultures was carried out using the Gorilla algorithm (), on two unranked lists of proteins, with a P-value threshold of 0.001. The list of proteins quantified in six out of six samples in the two experiments (3090 for the tissue vs. sh […]


Non Pleiotropic Coupling of Daily and Seasonal Temporal Isolation in the European Corn Borer

PMCID: 5924522
PMID: 29587435
DOI: 10.3390/genes9040180

[…] ions. Enriched gene ontology (GO) terms were identified for differentially expressed transcripts. This was done using the FlyBase D. melanogaster gene IDs [] derived from the annotated gene pairs and GOrilla []. GO enrichment was performed only for transcripts that were also differentially expressed between strains during diapause break. We also searched for previous identified olfactory receptor […]


Ligand Binding Site Structure Influences the Evolution of Protein Complex Function and Topology

Cell Rep
PMCID: 5873459
PMID: 29562182
DOI: 10.1016/j.celrep.2018.02.085

[…] eneric tool for term-enrichment analysis of ranked lists. Enriched terms (after correction for multiple testing with FDR) were visualized with a method conceptually similar to the graphical output of GOrilla (), with directed graphs and using color coding to indicate the significance of the enrichment, the intensity of red indicating significance. Graphs were drawn using GraphViz. […]


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GOrilla institution(s)
Molecular Cell Biology Department, Weizmann Institute of Science, Rehovot, Israel

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