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GOToolBox specifications


Unique identifier OMICS_04140
Name GOToolBox
Interface Web user interface
Restrictions to use Academic or non-commercial use
Computer skills Basic
Stability Stable
Maintained Yes

Publication for GOToolBox

GOToolBox citations


Fank1 and Jazf1 promote multiciliated cell differentiation in the mouse airway epithelium

PMCID: 5936064
PMID: 29661797
DOI: 10.1242/bio.033944

[…] hips (five chips per condition). Data were analysed using the Bioconductor Package in R and raw data deposited in Gene Expression Omnibus (GEO) (GSE111300). Gene Ontology analysis was performed using GOToolbox ( The E11.5 tip microarray data have been previously published () and the raw data are available at GEO (GSE75860). […]


Decreased Brain pH as a Shared Endophenotype of Psychiatric Disorders

PMCID: 5770757
PMID: 28776581
DOI: 10.1038/npp.2017.167
call_split See protocol

[…] ts (yielding 80 features; ) were selected based on the criteria of the BaseSpace tool and assessed for enrichment in biological themes using the DAVID functional annotation clustering tool, ADGO, and GOToolBox, in which the default feature listings and algorithm settings were used. […]


Upregulation of the Nr2f1 A830082K12Rik gene pair in murine neural crest cells results in a complex phenotype reminiscent of Waardenburg syndrome type 4

PMCID: 5117235
PMID: 27585883
DOI: 10.1242/dmm.026773
call_split See protocol

[…] false discovery rate (Benjamini–Hochberg) procedure. For the GO analysis, only differentially-expressed genes with an adjusted edgeR P-value ≤0.001 were included. The GO analysis was performed using GOToolBox ( with enriched categories selected from a hypergeometric test based on a Benjamini–Hochberg-corrected P-value threshold of 0.05. REVIGO ( […]


Lung epithelial tip progenitors integrate glucocorticoid and STAT3 mediated signals to control progeny fate

PMCID: 5087639
PMID: 27578791
DOI: 10.1242/dev.134023

[…] ybridisation to Affymetrix mouse 430.2 microarray chips (five chips per condition). Data were analysed using the Bioconductor Package in R (; ). Gene Ontology analysis using GOToolbox ( Raw data was deposited in GEO ( under accession number GSE75860. […]


A de novo transcriptome analysis shows that modulation of the JAK STAT signaling pathway by salmonid alphavirus subtype 3 favors virus replication in macrophage/dendritic like TO cells

BMC Genomics
PMCID: 4878077
PMID: 27215196
DOI: 10.1186/s12864-016-2739-6

[…] The first generation of pathway analytical softwares comprise of the over-representation analysis (ORA) softwares that include GenMAPP (, GOstat ( and GOToolBox ( These software establish pathway analysis by putting together over expressed genes that show significant changes in expression based on gene level statisti […]


The heat shock response restricts virus infection in Drosophila

Sci Rep
PMCID: 4522674
PMID: 26234525
DOI: 10.1038/srep12758
call_split See protocol

[…] eier analyses and log-rank tests, as implemented in SPSS Statistics (version 20, IBM). P-values below 0.05 were considered statistically significant. Enrichment of Gene Ontology terms was analysed in GoToolBox, using the hypergeometric test with Benjamini & Hochberg correction. […]


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GOToolBox institution(s)
Laboratoire de Génétique et Physiologie du Développement, IBDM, CNRS/INSERM/Université de la Méditerranée, Parc Scientifique de Luminy, Marseille, France

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